Kaerophyllin CAS 75590-33-9

Introduction:Basic information about Kaerophyllin CAS 75590-33-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Kaerophyllin Basic information

Product Name:Kaerophyllin
Synonyms:Kaerophyllin;(-)-Kaerophylin;Chaerophyllin;2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methylene]dihydro-, (3E,4R)-
CAS:75590-33-9
MF:C21H20O6
MW:368.38
EINECS:
Product Categories:
Mol File:75590-33-9.mol

Kaerophyllin Chemical Properties

solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder

Safety Information

Kaerophyllin Usage And Synthesis

DescriptionKaerophyllin can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression. Kaerophyllin inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.
UsesKaerophyllin ((-)-Kaerophylin) is a lignan that can be found in Chaerophyllum maculatum[1].
targetTNF-α | PPAR | Akt | ERK | NF-kB | IL Receptor
References[1] Mikaya GA, et al. Kaerophyllin, a new lignan from Chaerophyllum maculatum. Planta Med. 1981 Dec;43(4):378-80. DOI:10.1055/s-2007-971527

Kaerophyllin Preparation Products And Raw materials

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