Introduction:Basic information about Kaerophyllin CAS 75590-33-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Kaerophyllin Basic information
| Product Name: | Kaerophyllin |
| Synonyms: | Kaerophyllin;(-)-Kaerophylin;Chaerophyllin;2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methylene]dihydro-, (3E,4R)- |
| CAS: | 75590-33-9 |
| MF: | C21H20O6 |
| MW: | 368.38 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 75590-33-9.mol |
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Kaerophyllin Chemical Properties
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
Safety Information
Kaerophyllin Usage And Synthesis
| Description | Kaerophyllin can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression. Kaerophyllin inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity. |
| Uses | Kaerophyllin ((-)-Kaerophylin) is a lignan that can be found in Chaerophyllum maculatum[1]. |
| target | TNF-α | PPAR | Akt | ERK | NF-kB | IL Receptor |
| References | [1] Mikaya GA, et al. Kaerophyllin, a new lignan from Chaerophyllum maculatum. Planta Med. 1981 Dec;43(4):378-80. DOI:10.1055/s-2007-971527 |
Kaerophyllin Preparation Products And Raw materials