L-1-Phenylethylamine CAS 2627-86-3

Introduction：Basic information about L-1-Phenylethylamine CAS 2627-86-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

L-1-Phenylethylamine Basic information

• Product Name: L-1-Phenylethylamine
• Synonyms: (-)-alpha-Phenethylamine;(S)-alpha-Methylbenzenemethanamine;Tetra-SodiumPyrophosph;(1S)-(-)-1-Phenylethylamine 99%;(s)-benzenemethanamin;(S)-1-Amino-1-phenylethane;(S)-(-)-ALPHA-METHYLBENZYLAMINE;S-(-)-ALPHA-PHENYLETHYLAMINE
• CAS: 2627-86-3
• MF: C8H11N
• MW: 121.18
• EINECS: 220-098-0
• Product Categories: Amines (Chiral);Analytical Chemistry;Asymmetric Synthesis;Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;for Resolution of Acids;Optical Resolution;chiral;Amines;Aromatics;Chiral Reagents;Synthetic Organic Chemistry;Chiral Compound;2627-86-3
• Mol File: 2627-86-3.mol

L-1-Phenylethylamine Chemical Properties

• Melting point: -10 °C
• alpha: -40 º (neat)
• Boiling point: 187 °C(lit.)
• density: 0.94 g/mL at 25 °C(lit.)
• vapor pressure: 0.5 mm Hg ( 20 °C)
• refractive index: n20/D 1.526(lit.)
• Fp: 175 °F
• storage temp.: 2-8°C
• solubility: 42g/l
• pka: 9.04±0.10(Predicted)
• form: Liquid
• color: Clear colorless
• PH: >7 (H2O, 20°C) (undiluted)
• Optical Rotation: [α]20/D 39°, neat
• Water Solubility: slightly soluble
• Sensitive: Air Sensitive
• Merck: 14,6026
• BRN: 2204907
• InChI: 1S/C8H11N/c1-7(9)8-5-3-2-4-6-8/h2-7H,9H2,1H3/t7-/m0/s1
• InChIKey: RQEUFEKYXDPUSK-ZETCQYMHSA-N
• SMILES: C[C@H](N)c1ccccc1
• LogP: 1.31 at 25℃
• CAS DataBase Reference: 2627-86-3(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, «alpha»-methyl-, (S)-(2627-86-3)
• EPA Substance Registry System: Benzenemethanamine, .alpha.-methyl-, (.alpha.S)- (2627-86-3)

Safety Information

• Hazard Codes: C,Xi
• Risk Statements: 21/22-34-35
• Safety Statements: 26-28-36/37/39-45-28A-27
• RIDADR: UN 2922 8/PG 2
• WGK Germany: 1
• RTECS: DP5775000
• F: 3-10-23-34
• Autoignition Temperature: 355 °C
• Hazard Note: Irritant
• TSCA: TSCA listed
• HazardClass: 8
• PackingGroup: III
• HS Code: 29214980
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
• Hazard Classifications: Acute Tox. 3 Dermal Acute Tox. 4 Oral Skin Corr. 1B
• Toxicity: LD50 orally in Rabbit: 980 mg/kg LD50 dermal Rabbit 730 mg/kg

L-1-Phenylethylamine Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(-)-1-Phenylethylamine is utilized in a one-pot, multi-component synthesis of a highly substituted, chiral pyrrole.

Uses

Used in a one-pot, multi-component synthesis of a highly substituted, chiral pyrrole.

Uses

L-1-Phenylethylamine can be used in a one-pot, multi-component synthesis of a highly substituted, chiral pyrrole

Definition

ChEBI: The (S)-enantiomer of 1-phenylethanamine.

General Description

(S)-(?)-α-Methylbenzylamine is a chiral derivatizing agent, which is employed for derivatizing enantiomers into diastereoisomers.

Flammability and Explosibility

Non flammable

Toxics Screening Level

The ITSL for L-alpha-phenylethylamine is 0.1 μg/m3 based on an annual averaging time.

L-1-Phenylethylamine Preparation Products And Raw materials

• Raw materials: Sodium hydroxide-->Methanol-->Diethyl ether-->L(+)-Tartaric acid-->DL-alpha-Methylbenzylamine
• Preparation Products: (R)-(+)-2-Methyl-2-propanesulfinamide-->(S)-(-)-2-Azetidinecarboxylic acid-->(R)-(+)-1,1'-Bi-2-naphthol-->(R)-3-Aminoquinuclidine dihydrochloride-->(S)-(-)-1,1'-Bi-2-naphthol-->(R)-(+)-BORNYLAMINE-->Esfenvalerate-->(-)-BIS[(S)-1-PHENYLETHYL]AMINE HYDROCHLORIDE-->(S)-(-)-N-Benzyl-1-phenylethylamine-->(-)-Bis[(S)-1-phenylethyl]amine-->(R)-(+)-N-Benzyl-1-phenylethylamine-->(S)-(-)-N,ALPHA-DIMETHYLBENZYLAMINE-->(S)-(-)-1-Phenylethyl isocyanate-->2,2,2-TRIFLUORO-N-[(S)-ALPHA-METHYLBENZYL]ACETAMIDE