Introduction：Basic information about Lascufloxacin CAS 848416-07-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Lascufloxacin Basic information
| Product Name: | Lascufloxacin |
| Synonyms: | KRP-AM1977X;3-Quinolinecarboxylic acid, 7-[(3S,4S)-3-[(cyclopropylamino)methyl]-4-fluoro-1-pyrrolidinyl]-6-fluoro-1-(2-fluoroethyl)-1,4-dihydro-8-methoxy-4-oxo-;KRP-AM1977;Lascufloxacin |
| CAS: | 848416-07-9 |
| MF: | C21H24F3N3O4 |
| MW: | 439.43 |
| EINECS: | |
| Product Categories: | API |
| Mol File: | 848416-07-9.mol |
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Lascufloxacin Chemical Properties
| Boiling point | 637.0±55.0 °C(Predicted) |
| density | 1.44±0.1 g/cm3(Predicted) |
| solubility | Chloroform (Slightly), DMSO (Very Slightly) |
| form | Solid |
| pka | 6.29±0.50(Predicted) |
| color | White to Off-White |
Safety Information
Lascufloxacin Usage And Synthesis
| Uses | Lascufloxacin is an intermediate used in the preparation of quinolonecarboxylic acid deriatives as antibacterial agents. |
| in vivo | A pharmacodynamic study using a mouse thigh infection model indicates that the ratios of the free area under the curve (fAUC) to MIC in plasma required for bacteriostasis, or 1-log or 2-log CFU killing against S. pneumoniae isolates, are 10, 16, and 28, respectively. Lascufloxacin shows significant bacterial killing in the mouse model when emulated the area under the concentration-time curve (AUC) in plasma in dose of 75 mg per day [q.d.]) [2]. |
| IC 50 | Quinolone |
Lascufloxacin Preparation Products And Raw materials
