Macrocarpal C CAS 142628-53-3

Introduction：Basic information about Macrocarpal C CAS 142628-53-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Macrocarpal C Basic information

• Product Name: Macrocarpal C
• Synonyms: 1,3-Benzenedicarboxaldehyde,5-[(1R)-1-[(1aR,4aR,7S,7aR,7bR)-decahydro-1,1,7-trimethyl-4-methylene-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy-;Macrocarpal C;Macrocarpal C/G;5-[(1R)-1-[(1aR,4aR,7S,7aR,7bR)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxybenzene-1,3-dicarbaldehyde
• CAS: 142628-53-3
• MF: C28H38O5
• MW: 454.6
• Product Categories: Sesquiterpenoids
• Mol File: 142628-53-3.mol

Macrocarpal C Chemical Properties

• Boiling point: 509.6±50.0 °C(Predicted)
• density: 1.20±0.1 g/cm3(Predicted)
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• form: powder
• pka: 5.40±0.50(Predicted)
• color: Yellow

Macrocarpal C Usage And Synthesis

Description

Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purification, the antifungal action of macrocarpal C was associated with increases of membrane permeability, intracellular ROS and DNA fragmentation.

Uses

Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation[1].

Definition

ChEBI: Macrocarpal C is a sesquiterpenoid.

target

ROS | Antifection

References

[1] Jack Ho Wong, et al. Antifungal mode of action of macrocarpal C extracted from Eucalyptus globulus Labill (Lan An) towards the dermatophyte Trichophyton mentagrophytes. Chin Med. 2015, 10, 34.