Introduction：Basic information about MAF CAS 101365-54-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
MAF Basic information
| Product Name: | MAF |
| Synonyms: | Ferric methylarsonate;Methoxyacetyl fentanyl hydrochloride solution;good quality 99.5% MAF with lowest price;MAF 5F-MDMB-2201 methoxyaceylfentanyl;MAF power;MAF;IFN-γ human;Immune Interferon |
| CAS: | 101365-54-2 |
| MF: | C22H29ClN2O2 |
| MW: | 388.94 |
| EINECS: | |
| Product Categories: | pharmaceutical intermediates;research chemical;Chemical and pharmaceutical intermediates;Medical research;pharmaceutical intermediate or chemical research |
| Mol File: | Mol File |
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MAF Chemical Properties
| storage temp. | -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml; Methanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml |
| form | A neat solid |
| color | white to off-white |
| biological source | human |
| Stability: | Hygroscopic |
Safety Information
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
MAF Usage And Synthesis
| Uses | IFN-γ (interferon γ)-human has been used for the generation of inflammatory M1 cells from human monocytic cell line, THP1. |
| General Description | IFN-γ (interferon γ) is an acid-labile glycosylated interferon produced by CD4 and CD8 T lymphocytes as well as activated NK (natural killer) cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC (major histocompatibility complex) proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. The gene is mapped to human chromosome 12q15. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7kDa protein containing 143 amino acid residues. |
| Biochem/physiol Actions | IFN-γ (interferon γ) signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. It can suppress the generation of anti-inflammatory cytokines and enhance the secretion of proinflammatory cytokines. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK (natural killer) cells and neutrophils. It is responsible for tumor rejection and is capable of killing tumor cells by autophagy or apoptosis. IFN-γ is also involved in Hepatitis E virus disease pathogenesis. |
MAF Preparation Products And Raw materials
