Mannioside A CAS 1038922-95-0

Introduction：Basic information about Mannioside A CAS 1038922-95-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Mannioside A Basic information

• Product Name: Mannioside A
• Synonyms: (25R)-17α-hydroxyspirost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1→3)-β-D-glucopyranoside;Mannioside A;(3beta,25R)-17-Hydroxyspirost-5-en-3-yl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside;β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-
• CAS: 1038922-95-0
• MF: C39H63O13
• MW: 739.90972
• Mol File: 1038922-95-0.mol

Mannioside A Usage And Synthesis

Uses

Mannioside A is a steroidal saponin. Mannioside A is a nature product that could be isolated from Dracaena mannii. Mannioside A has anti-inflammatory effect[1].

Definition

ChEBI: Mannioside A is a steroid saponin that consists of pennogenin attached to alpha-L-rhamnopyranosyl-(1->3)-beta-D-glucopyranosyl residue at position 3 via a glycoidic linkage. Isolated from Dracaena mannii, it exhibits anti-inflammatory activity. It has a role as a metabolite and an anti-inflammatory agent. It is a 17alpha-hydroxy steroid, an organic heterohexacyclic compound, an oxaspiro compound, a disaccharide derivative and a steroid saponin. It is functionally related to a pennogenin.

in vivo

Mannioside A (compound 1; 10 mg/kg; p.o.) inhibits carrageene-induced paw edema in rats^[1].

• Animal Model: Wistar rats^[1]
• Dosage: 10 mg/kg
• Administration: oral administration
• Result: Had anti-inflammatory effects with maximum activity observed within 2 h.

References

[1] Tapondjou LA, et, al. In vivo anti-inflammatory effect of a new steroidal saponin, mannioside A, and its derivatives isolated from Dracaena mannii. Arch Pharm Res. 2008 May;31(5):653-8. DOI:10.1007/s12272-001-1208-3