Methylglucamine antimonate CAS 133-51-7

Introduction：Basic information about Methylglucamine antimonate CAS 133-51-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Methylglucamine antimonate Basic information

• Product Name: Methylglucamine antimonate
• Synonyms: 1-deoxy-1-(methylamino)-,compd.withantimonicacid(1:1),d-glucito;1-deoxy-1-(methylamino)-d-glucitocompd.withantimonicacid(1:1);1-deoxy-1-(methylamino)-d-glucitotrioxoantimonate(1-);2168-rp;glucantime;meglumineantimonate;methylglucamineantimonate;protostib
• CAS: 133-51-7
• MF: C7H18NO8Sb
• MW: 365.98
• EINECS: 205-108-3
• Mol File: 133-51-7.mol

Methylglucamine antimonate Chemical Properties

• storage temp.: Refrigerator, Under inert atmosphere
• solubility: Acidic DMSO (Slightly, Sonicated), Aqueous Base (Very Slightly, Heated)
• form: Solid
• color: White to Off-White
• InChI: InChI=1/C7H17NO5.3O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;;;;/q;;;;-1/p+1/t4-,5+,6+,7+;;;;/s3
• InChIKey: JLGCKKAHTCRITP-GZLWXHMYNA-O
• SMILES: [C@@H](O)([C@@H](O)CNC)[C@H](O)[C@H](O)CO.[Sb-](=O)(=O)=O.[H+] |&1:0,2,7,9,r|
• CAS DataBase Reference: 133-51-7(CAS DataBase Reference)
• EPA Substance Registry System: Glucantime (133-51-7)

Methylglucamine antimonate Usage And Synthesis

Uses

In the synthesis of surface active agents, pharmaceuticals, dyes.

Pharmaceutical Applications

N-Methylglucamine antimonate; methylaminoglucitol antimonate.The Sb^V content varies around 28% between batches.The major moieties are Sb^V–ligand complexes which are zwitterionicin solution.The activity, pharmacology and toxicology are similar tothose of sodium stibogluconate, with which it is essentiallyinterchangeable.

Clinical Use

Treatment of visceral and cutaneous leishmaniasis
Studies in Central and South America have indicated that thecombination with interferon-γ is effective in the treatment ofvisceral and cutaneous leishmaniasis cases unresponsive toantimony alone.