Introduction：Basic information about Metyltetraprole CAS 1472649-01-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Metyltetraprole Basic information
| Product Name: | Metyltetraprole |
| Synonyms: | 1-[2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)-3-methylphenyl]-4-methyl-1,4-dihydro-5H-tetrazol-5-one: metyltetraprole;Metyltetraprole;5H-Tetrazol-5-one, 1-[2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]-3-methylphenyl]-1,4-dihydro-4-methyl-;Metyltetraprole 100 μg/ml Acetonitrile;Metyltetraprole 100.0 μg/ml Acetonitrile;Metyltetraprole 100 μg/mL in Acetonitrile |
| CAS: | 1472649-01-6 |
| MF: | C19H17ClN6O2 |
| MW: | 396.83 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 1472649-01-6.mol |
|
Metyltetraprole Chemical Properties
| Boiling point | 536.9±60.0 °C(Predicted) |
| density | 1.40±0.1 g/cm3(Predicted) |
| pka | -0.23±0.10(Predicted) |
Safety Information
Metyltetraprole Usage And Synthesis
| Uses | Metyltetraprole is a promising fungicide with EC50 values of both 0.002 ppm against sensitive wild-type and G143A mutant of Zymoseptoria tritici. Metyltetraprole is effective against QoI (quinone outside inhibitor) resistant strains. Metyltetraprole inhibits the respiratory chain via complex III[1][2]. |
| Definition | ChEBI: Metyltetraprole is a member of the class of tetrazoles that is 1-methyl-4-phenyltetrazole in which the phenyl group has been substituted at positions 2 and 3 by [1-(p-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl and methyl groups, respectively. A quinone outside inhibitor, it is a fungicide that can be used to control a broad range of diseases, including Septoria leaf blotch in wheat. It has a role as an antifungal agrochemical and a quinone outside inhibitor. It is a member of tetrazoles, a pyrazole pesticide and a member of monochlorobenzenes. |
| References | [1] Matsuzaki Y, et al. Discovery of metyltetraprole: Identification of tetrazolinone pharmacophore to overcome QoI resistance. Bioorg Med Chem. 2020 Jan 1;28(1):115211. DOI:10.1016/j.bmc.2019.115211
[2] Suemoto H, et al. Metyltetraprole, a novel putative complex III inhibitor, targets known QoI-resistant strains of Zymoseptoria tritici and Pyrenophora teres. Pest Manag Sci. 2019 Apr;75(4):1181-1189. DOI:10.1002/ps.5288 |
Metyltetraprole Preparation Products And Raw materials
