MONOLAURIN CAS 142-18-7

Introduction：Basic information about MONOLAURIN CAS 142-18-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

MONOLAURIN Basic information

• Product Name: MONOLAURIN
• Synonyms: alpha-Monolaurin;Dodecanoicacid,2,3-dihydroxypropylester;dodecanoicacid2,3-dihydroxy-propylester;dodecanoicacidalpha-monoglyceride;glucerolalpha-monolaurate;Glycerin 1-monolaurate;lauricacid1-monoglyceride;lauricacidalpha-monoglyceride
• CAS: 142-18-7
• MF: C15H30O4
• MW: 274.4
• EINECS: 205-526-6
• Product Categories: Other APIs
• Mol File: 142-18-7.mol

MONOLAURIN Chemical Properties

• Melting point: 63 °C
• Boiling point: 186 °C / 1mmHg
• density: 0.9764 (rough estimate)
• refractive index: 1.4350 (estimate)
• storage temp.: -20°C
• solubility: Practically insoluble in water
• pka: 13.16±0.20(Predicted)
• form: powder to crystal
• color: White to Almost white
• biological source: plant
• Water Solubility: 6mg/L
• BRN: 1726740
• Cosmetics Ingredients Functions: SKIN CONDITIONING - EMOLLIENT SURFACTANT - EMULSIFYING
• Cosmetic Ingredient Review (CIR): MONOLAURIN (142-18-7)
• InChI: 1S/C15H30O4/c1-2-3-4-5-6-7-8-9-10-11-15(18)19-13-14(17)12-16/h14,16-17H,2-13H2,1H3
• InChIKey: ARIWANIATODDMH-UHFFFAOYSA-N
• SMILES: CCCCCCCCCCCC(=O)OCC(O)CO
• LogP: 4.029 (est)
• CAS DataBase Reference: 142-18-7(CAS DataBase Reference)
• EPA Substance Registry System: 1-Monolaurin (142-18-7)

Safety Information

• WGK Germany: 1
• RTECS: OF1600000
• TSCA: TSCA listed
• HS Code: 2918.19.9000
• Storage Class: 11 - Combustible Solids

MONOLAURIN Usage And Synthesis

Uses

glyceryl laurate is a coemulsifier for oil-in-water emulsions. It is also a super fattening agent that promotes absorption and has a bacteriostatic effect.

Uses

Monolaurin has antibacterial, antiviral, and other antimicrobial effects in vitro.

Definition

ChEBI: 1-monolauroylglycerol is a 1-monoglyceride with dodecanoyl (lauroyl) as the acyl group. It is a 1-monoglyceride and a dodecanoate ester.

Synthesis Reference(s)

Synthetic Communications, 19, p. 2505, 1989 DOI: 10.1080/00397918908052653

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Monolaurin (1-Lauroyl-rac-glycerol) is used as an antimicrobial agent in various formulas and microemulsions and as a methane mitigation agent in ruminants.

Synthesis

(1)Use lower alcohol Na or lower alcohol potassium as catalyst, lower alcohol ester of lauric acid and glycerol mixed according to the molar ratio of 3:1, under the condition of 150-170 ?? vacuum reaction 20-40h to obtain glycerol ester of lauric acid crude product;

(2)Use 40-50% of the weight of the crude product of glycerol ester of fatty lauric acid, mass fraction of 4%-10% of the aqueous citric acid to wash fatty acid glycerol ester of crude product once, and then Add 30% -50% of the weight of crude glyceryl laurate 80-100 ?? C hot water, stirred well, static stratification, separation of the upper layer of oil, and then 80-100 ?? C hot water, water wash 3 times, heating and depressurization to remove water;

(3) in the temperature of 130-220 ?? C, the vacuum degree of 0.1-150pa under the conditions of molecular distillation of the product of the said step (2) to get the product of the glyceryl laurate. Glyceryl laurate product.