N-Ethyl-N-hydroxyethylaniline CAS 92-50-2

Introduction：Basic information about N-Ethyl-N-hydroxyethylaniline CAS 92-50-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

N-Ethyl-N-hydroxyethylaniline Basic information

• Product Name: N-Ethyl-N-hydroxyethylaniline
• Synonyms: 2-(Ethylanilino)ethanol;2-(ethylphenylamino)-ethano;2-(N-Ethyl-N-phenylamino)ethanol;N-ETHYL-N-PHENYLETHANOLAMINE;N-(B-HYDROXYETHYL)-N-ETHYLANILINE;N-Ethyl-N-hydroxyethylaniline, 96% 100GR;2-[Phenyl(ethyl)amino]ethanol;N-Ethyl-N-hydroxyethylaniline,96%
• CAS: 92-50-2
• MF: C10H15NO
• MW: 165.23
• EINECS: 202-160-9
• Product Categories: aniline derivatives;Amino Alcohols;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;organic chemical;Amino Alcohols;Organic Building Blocks;Oxygen Compounds;Intermediates of Dyes and Pigments
• Mol File: 92-50-2.mol

N-Ethyl-N-hydroxyethylaniline Chemical Properties

• Melting point: 36-38 °C (lit.)
• Boiling point: 268 °C (lit.)
• density: 1.02
• vapor pressure: 1Pa at 25℃
• refractive index: 1.5605-1.5625
• Fp: 120 °C
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 14.66±0.10(Predicted)
• form: Liquid
• color: Clear colorless to yellow to orange, product may darken in storage
• Water Solubility: 4.975g/L(20 ºC)
• InChI: 1S/C10H15NO/c1-2-11(8-9-12)10-6-4-3-5-7-10/h3-7,12H,2,8-9H2,1H3
• InChIKey: HYVGFUIWHXLVNV-UHFFFAOYSA-N
• SMILES: CCN(CCO)c1ccccc1
• LogP: 1.88 at 20℃
• CAS DataBase Reference: 92-50-2(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-(ethylphenylamino)-(92-50-2)
• EPA Substance Registry System: Ethanol, 2-(ethylphenylamino)- (92-50-2)

Safety Information

• Hazard Codes: Xn
• Risk Statements: 22-36/37/38-36
• Safety Statements: 36/37/39-39-26
• WGK Germany: 2
• RTECS: KL0878000
• TSCA: TSCA listed
• HS Code: 29221990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

N-Ethyl-N-hydroxyethylaniline Usage And Synthesis

Chemical Properties

clear yellow liquid after melting

Uses

2-(N-Ethylanilino) ethanol was used in the preparation of azo compound N-ethyl-N-(2-hydroxylethyl)-4-(2-cyano-4-nitrophenylazo) aniline (AZ1)².

General Description

2-(N-Ethylanilino) ethanol couples with 2-amino-5-formylthiophene during the synthesis of nonlinear optical chromophores. It undergoes azo coupling with 2-cyan-4-nitroaniline to yield azochromophore AZ1.

Synthesis

75-21-8

103-69-5

92-50-2

1. The autoclave was purged with nitrogen and protected by nitrogen with 24.2 kg (200 mol) of N-ethylaniline, 8.9 kg (202 mol) of ethylene oxide, and 242 g (1.9 mol) of taurine. 2. The autoclave was closed, making sure that the lid was screwed on tightly. 3. The heating system was turned on, and the temperature was ramped up to 102°C at a rate of 1°C/min before stopping the heating, and the temperature of the reaction will naturally rise to 133°C. 4. Maintain the reaction at 133°C for 4 h. 5. Upon completion of the reaction, the reaction mixture was cooled to 40°C. 6. Open the autoclave and collect the product to give 32.8 kg of N-ethyl-N-hydroxyethylaniline in 99.4% yield.

References

[1] Patent: CN108117492, 2018, A. Location in patent: Paragraph 0050; 0052; 0054; 0056; 0057; 0058
[2] Journal of the American Chemical Society, 1944, vol. 66, p. 1640
[3] Bulletin de la Societe Chimique de France, 1927, vol. <4>41, p. 937

N-Ethyl-N-hydroxyethylaniline Preparation Products And Raw materials

• Raw materials: ETHYLENE OXIDE-->N-Ethylaniline
• Preparation Products: BASIC BLUE 41 (C.I. 11105)-->2-[ethyl[3-methyl-4-[(5-nitrothiazol-2-yl)azo]phenyl]amino]ethanol-->DISPERSE RED 13-->N-Chloroethyl-N-ethylaniline-->p-[[p-[ethyl(2-hydroxyethyl)amino]phenyl]azo]benzenesulphonamide-->BASIC BLUE 41-->DISPERSE RED 13-->AMACEL ORANGE 4R-->Disperse Red 1-->Disperse Orange 23-->Disperse Red 8-->Disperse orange 50-->2-(ethylphenylamino)ethyl acetate