Introduction：Basic information about N-Methylacetoacetamide CAS 20306-75-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-Methylacetoacetamide Basic information
| Product Name: | N-Methylacetoacetamide |
| Synonyms: | Acetoacet-monomethylamide;AcetoN-methylacetamide;Butanamide,N-methyl-3-oxo-;n-methyl-3-oxo-butanamid;Arbidol Impurity 7;N-ACETOACETYLMETHYLAMINE;N-METHYLACETOACETAMIDE: (CA. 65% IN WATER);N-Methylacetoacetamide (ca. 70% in Water) |
| CAS: | 20306-75-6 |
| MF: | C5H9NO2 |
| MW: | 115.13 |
| EINECS: | 243-723-9 |
| Product Categories: | ACETYLGROUP |
| Mol File: | 20306-75-6.mol |
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N-Methylacetoacetamide Chemical Properties
| Melting point | -3 °C |
| Boiling point | 106°C |
| density | 1.069 |
| refractive index | 1.4325-1.4345 |
| Fp | 105 °C |
| storage temp. | 2-8°C |
| solubility | hydrolysis |
| form | clear liquid |
| pka | 12.79±0.46(Predicted) |
| color | Light yellow to Yellow to Orange |
| Water Solubility | hydrolysis |
| CAS DataBase Reference | 20306-75-6(CAS DataBase Reference) |
| EPA Substance Registry System | Butanamide, N-methyl-3-oxo- (20306-75-6) |
Safety Information
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25 |
| TSCA | TSCA listed |
| HS Code | 2924297099 |
N-Methylacetoacetamide Usage And Synthesis
| Chemical Properties | Colourless to yellowish clear liquid |
| Uses | N-Methylacetoacetamide (min. 70% in water) (MMAA) is used as intermediate for the manufacture of insecticides, e.g. monocrotophos Product Data Sheet |
| Uses | N-Methylacetoacetamide is a starting material in the synthesis of 1-Carbamoyl-2-oxopropyl acetate with the aid (diacetoxyiodo)benzene (DIB) as the oxidant. Also, it is a reagent used in the synthesis of 10H-Phenothiazines, which possesses for their biological activity against the regulatory enzymes involved in inflammatory diseases. |
| Definition | ChEBI: N-Methylacetoacetamide is a fatty amide. |
N-Methylacetoacetamide Preparation Products And Raw materials
| Raw materials | Methylamine-->Acetyl ketene-->METHANE |
| Preparation Products | 2-CHLORO-N-METHYLACETOACETAMIDE-->Monocrotophos-->Amlodipine Impurity 42 |
