Introduction：Basic information about N-Nicotinoylglycine CAS 583-08-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-Nicotinoylglycine Basic information
| Product Name: | N-Nicotinoylglycine |
| Synonyms: | NICOTINYLGLYCINE;NICOTINOYL-GLYCINE;NICOTINOYL-GLY-OH;NICOTINURIC ACID;NICOTINICAMIDO ACETIC ACID;N-NicotinuricAcid~99%;N-Nicotinuricacid;Nicotinuric |
| CAS: | 583-08-4 |
| MF: | C8H8N2O3 |
| MW: | 180.16 |
| EINECS: | 209-497-0 |
| Product Categories: | Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Aromatics;Heterocycles;Amino Acids |
| Mol File: | 583-08-4.mol |
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N-Nicotinoylglycine Chemical Properties
| Melting point | 256-2580C (dec.) |
| Boiling point | 85-90 °C(Press: 12-20 Torr) |
| density | 1.49 g/cm3 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 3.10±0.10(Predicted) |
| color | White to Off-White |
| Water Solubility | Soluble in dimethyl sulfoxide, methanol, water, and 1M NH4OH (50 mg/mL). |
| InChI | 1S/C8H8N2O3/c11-7(12)5-10-8(13)6-2-1-3-9-4-6/h1-4H,5H2,(H,10,13)(H,11,12) |
| InChIKey | ZBSGKPYXQINNGF-UHFFFAOYSA-N |
| SMILES | OC(=O)CNC(=O)c1cccnc1 |
| CAS DataBase Reference | 583-08-4(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| WGK Germany | 3 |
| HS Code | 2933.39.9200 |
| HazardClass | IRRITANT |
| Storage Class | 11 - Combustible Solids |
N-Nicotinoylglycine Usage And Synthesis
| Chemical Properties | White Solid |
| Uses | N-Nicotinoylglycine can be used to antiproliferative and as a Niacin analog for therapeutic use. |
| Uses | A Niacin analog for therapeutic use. Antiproliferative. |
| Definition | ChEBI: An N-acylglycine having nicotinoyl as the acyl substituent. |
| Biological Activity | Nicotinuric acid (NUA) is a metabolite of niacin/vitamin B. Measurement of NUA levels in urine is used to indicate possible elevated nicotinamide adenine dinucleotide (NAD) catabolism. NUA may be used as a reference (standard curve) in the analysis of NAD and NUA catabolism. Nicotinic acid reduces triglycerides and increases high density lipoprotein(HDL) cholesterol. |
| IC 50 | Human Endogenous Metabolite |
N-Nicotinoylglycine Preparation Products And Raw materials
