Introduction：Basic information about n-Octyl-β-D-glucopyranoside CAS 29836-26-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
n-Octyl-β-D-glucopyranoside Basic information
| Product Name: | n-Octyl-β-D-glucopyranoside |
| Synonyms: | N-OCTYL GLUCOSIDE;N-OCTYL-B-D-GLUCOSIDE;N-OCTYL-BETA-D-GLC;N-OCTYL-BETA-D-GLUCOPYRANOSIDE;N-OCTYL-BETA-D-GLUCOSIDE;.beta.-D-Glucopyranoside, octyl;n-octyl-á-d-glucopyranoside;n-octyl-á-d-glucoside |
| CAS: | 29836-26-8 |
| MF: | C14H28O6 |
| MW: | 292.37 |
| EINECS: | 249-887-8 |
| Product Categories: | detergent;Carbohydrates & Derivatives;Detergents;Biochemistry;Glucose;Glycosides;Sugars;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Glycon Biochem |
| Mol File: | 29836-26-8.mol |
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n-Octyl-β-D-glucopyranoside Chemical Properties
| Melting point | 105 °C |
| alpha | -32 º (c=5, water) |
| Boiling point | 354.3°C (rough estimate) |
| density | 1.0869 (rough estimate) |
| refractive index | -27 ° (C=1, MeOH) |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Water (Slightly) |
| pka | 12.95±0.70(Predicted) |
| form | Crystalline Powder and Chunks |
| color | White |
| Water Solubility | 3 g/10 mL |
| Sensitive | Hygroscopic |
| Merck | 14,6767 |
| BRN | 84118 |
| Stability: | Hygroscopic |
| Cosmetics Ingredients Functions | SURFACTANT - CLEANSING
CLEANSING |
| Cosmetic Ingredient Review (CIR) | n-Octyl-β-D-glucopyranoside (29836-26-8) |
| InChI | 1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1 |
| InChIKey | HEGSGKPQLMEBJL-QNOVJUQQSA-N |
| SMILES | O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)OCCCCCCCC |
| LogP | 0.887 (est) |
| CAS DataBase Reference | 29836-26-8(CAS DataBase Reference) |
| EPA Substance Registry System | Octyl .beta.-D-glucopyranoside (29836-26-8) |
Safety Information
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29400090 |
| Storage Class | 13 - Non Combustible Solids |
n-Octyl-β-D-glucopyranoside Usage And Synthesis
| Description | n-Octyl-β-D-glucopyranoside is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. n-Octyl-β-D-glucopyranoside has a well–defined chemical structure, small uniform micelles, and high water solubility, which make n-Octyl-β-D-glucopyranoside superior to most other nonionic detergents for membrane solubilization. Because of the high critical micelle concentration (20-25 mM), n-Octyl-β-D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts. n-Octyl-β-D-glucopyranoside is also known as N-Octyl glucoside, OGP, OG, n-Octylglucoside, and octyl-β-D-glucopyranoside.
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| Chemical Properties | white crystalline powder and chunks |
| Uses | A nonionic detergent for the solubilization of membrane bound protein. |
| Uses | Unlike many other detergents, octyl glucoside is a pure, single compound of defined structure. Very effective for insulin binding and solubilization studies of membran |
| Uses | Detergent and surfactant for biological systems. |
| Definition | ChEBI: Octyl beta-D-glucopyranoside is an beta-D-glucoside in which the anomeric hydrogen of beta-D-glucopyranose is substituted by an octyl group. It has a role as a plant metabolite. |
| Purification Methods | Purify n-Octyl-β-D-glucopyranoside by recrystallisation from Me2CO. It is hygroscopic and should be stored in a well-stoppered container. [Noller & Rockwell J Am Chem Soc 6 0 2076 1938, Pigman & Richtmyer J Am Chem Soc 64 369 1942.] It is a UV transparent non-ionic dialysable detergent for solubilising membrane proteins. The D-isomer with [] D 20 +118o (c 1, MeOH) has similar solubilising properties. [Lazo & Quinn Anal Biochem 102 68 1980, Stubbs et al. Biochim Biophys Acta 426 46 1976, Beilstein 17/7 V 38.] |
n-Octyl-β-D-glucopyranoside Preparation Products And Raw materials
| Preparation Products | Octylb-D-glucuronicacid |
