Introduction：Basic information about Nsc670365 CAS 161753-49-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Nsc670365 Basic information
| Product Name: | Nsc670365 |
| Synonyms: | (+/-)-trans-Ketone;(1)-12-Oxocalanolide a;12-Oxocalanolide;151005-67-3 (Deleted);trans-10,11-Dihydro-6,6,10,11-tetramethyl-4-propyl-2H,6H,12H-benzo[1,2-b:3,4-b':5,6-b'']tripyran-2,12-dione;2H,6H,12H-Benzo[1,2-B:3,4-B':5,6-B'']tripyran-2,12-dione, 10,11-dihydro-6,6,10,11-tetramethyl-4-propyl-, (10R,11R)-rel-;Aids051610;Aids-051610 |
| CAS: | 161753-49-7 |
| MF: | C22H24O5 |
| MW: | 368.42 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 161753-49-7.mol |
|
Nsc670365 Chemical Properties
| Boiling point | 546.7±50.0 °C(Predicted) |
| density | 1.176±0.06 g/cm3(Predicted) |
Safety Information
Nsc670365 Usage And Synthesis
| Uses | 12-Oxocalanolide A (compound 6) is a potent inhibitor of reverse transcriptase from human immunodeficiency virus type 1 (HIV-1) with an IC50 and EC50 of 2.8 and 12 μM, respectively. 12-Oxocalanolide A is the analogue of Calanolide[1]. |
| IC 50 | HIV-1 |
| References | [1] Zembower DE, et al. Structural analogues of the calanolide anti-HIV agents. Modification of the trans-10,11-dimethyldihydropyran-12-ol ring (ring C). J Med Chem. 1997;40(6):1005-1017. DOI:10.1021/jm960355m |
Nsc670365 Preparation Products And Raw materials
