Introduction：Basic information about Ozagrel sodium CAS 189224-26-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Ozagrel sodium Basic information
| Product Name: | Ozagrel sodium |
| Synonyms: | OZAGREL SODIUM;(E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]acrylic acid sodium salt;Athrombone;D01684;Ozagrel sodium (jan);Ozapen;Ozapen (tn);sodium (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylate |
| CAS: | 189224-26-8 |
| MF: | C13H11N2NaO2 |
| MW: | 250.23 |
| EINECS: | 1806241-263-5 |
| Product Categories: | |
| Mol File: | 189224-26-8.mol |
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Ozagrel sodium Chemical Properties
| storage temp. | Store at -20°C |
| form | Solid |
| color | White to off-white |
| Water Solubility | Water: ≥ 44 mg/mL (175.84 mM) |
| InChI | InChI=1S/C13H12N2O2.Na/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;/h1-8,10H,9H2,(H,16,17);/q;+1/p-1/b6-5+; |
| InChIKey | NCNYJCOBUTXCBR-IPZCTEOASA-M |
| SMILES | [Na+].C([O-])(=O)/C=C/C1=CC=C(CN2C=NC=C2)C=C1 |
Safety Information
Ozagrel sodium Usage And Synthesis
| Chemical Properties | White powder |
| Uses | Ozagrel sodium (OKY-046 sodium) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel sodium is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM[1]. |
| IC 50 | TXA2 |
| References | [1] Max Seidy Saito, et al. Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1591-601. DOI:10.3109/14756366.2016.1158712 |
Ozagrel sodium Preparation Products And Raw materials
| Preparation Products | Ozagrel |
