Phenol Red CAS 143-74-8
Introduction：Basic information about Phenol Red CAS 143-74-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Phenol Red Basic information
| Product Name: | Phenol Red |
| Synonyms: | PHENOL REDRESEARCH GRADE;A-HYDROXY-A A-BIS(P-HYDROXYPHENYL)-O-TOLUENESULFONIC ACID G-SULTONE;3,3-BIS(P-HYDROXYPHENYL)-2,1-3H-BENZOXATHIOLE;SULFONAPHTHAL;TIMTEC-BB SBB006473;PR;PHENOSULFOHEPHTHALEIN INDICATOR;PHENOLSULFONPHTHALEIN |
| CAS: | 143-74-8 |
| MF: | C19H14O5S |
| MW: | 354.38 |
| EINECS: | 205-609-7 |
| Product Categories: | Stains and Dyes;P;Stains&Dyes, A to;General Stains/Dyes for Stem Cell BiologyStains and Dyes;PReagents and Supplements;Cell Culture;Cell Viability and Proliferation;In Vivo/In Vitro Tracking of Stem CellsStem Cell Biology;Stains, Dyes and Indicators;Stem Cell Biology;Stem Cell Characterization;Analytical Chemistry;Indicator (pH);pH Indicators;Sulfonephthalein |
| Mol File: | 143-74-8.mol |
Phenol Red Chemical Properties
| Melting point | >300 °C |
| Boiling point | >300°C |
| bulk density | 200-300kg/m3 |
| density | 1.445 Mg m-3 |
| refractive index | 1.5300 (estimate) |
| Fp | >300°C |
| storage temp. | no restrictions. |
| solubility | 1 M NaOH: soluble1mg/mL |
| form | Solid |
| pka | 7.9(at 25℃) |
| color | Red |
| PH Range | 6.6(YELLOW)-8.0(RED) |
| PH | 6.8～8.4 |
| Odor | Odorless |
| Water Solubility | 0.77 g/L |
| λmax | 557nm, 558nm, 360nm, 423nm, 433nm |
| ε(extinction coefficient) | ≥10000 at 288-294nm in H2O ≥55000 at 555-561nm in H2O ≥7000 at 357-363nm in H2O |
| Merck | 14,7247 |
| BRN | 326470 |
| Major Application | Display device, sol-gel matrix, photoreceptors, fuel cells, waveguides, paints, detergents, cosmetics, antiperspirant composition, diapers, screening bacteria, detecting viable cells, diagnosis of urogenital ureaplasmosis, treatment of pathogen infections, amyloid-associated diseases, glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud’s syndrome, heparin overdose, vulvodynia, wound healing, psychoactive drugs, evaluating dental caries activity |
| Cosmetics Ingredients Functions | BUFFERING |
| InChI | 1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H |
| InChIKey | BELBBZDIHDAJOR-UHFFFAOYSA-N |
| LogP | 3.020 |
| CAS DataBase Reference | 143-74-8(CAS DataBase Reference) |
| EPA Substance Registry System | Phenol Red (143-74-8) |
Safety Information
| Hazard Codes | Xi,C |
| Risk Statements | 36/37/38-34 |
| Safety Statements | 37/39-26-45-36/37/39-27 |
| WGK Germany | 3 |
| RTECS | SJ7490000 |
| TSCA | TSCA listed |
| HS Code | 29349990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Skin Irrit. 2 STOT SE 3 |
| Toxicity | LD50 orl-rat: >600 mg/kg CTOXAO 4(2),185,71 |
| Description | Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry. |
| Chemical Properties | dark red powder |
| Uses | As indicator in 0.02-0.05% alcohol solution. pH 6.8 yellow, 8.4 red. |
| Uses | Phenol red is used as a non absorbed marker in gravimetric method. It is a pH indicator used in cell biology laboratories and in home swimming pool test kits. It is used to check the kidney function based on the excreted phenol red by colorimetric method. |
| Uses | Phenol red solution acts as a pH indicator for the culture medium. |
| Application | Phenol red solution has been used: As a tracer dye for microinjection of zebrafish eggs. As a component of the mMW medium for preparation of mouse embryos. In the preparation of versene-ethylenediamine tetraacetic acid (EDTA) solution. |
| Preparation | Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline. |
| Definition | ChEBI: 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as anindicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney. |
| Biochem/physiol Actions | Phenol Red is a pH indicator which changes color from yellow to red. |
| Safety Profile | Moderately toxic by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxicvapors of SOx. |
| Enzyme inhibitor | This pH-indicating dye (FW = 354.38 g/mol; CAS 143-74-8; pKa = 7.9; yellow < pH 6.8; red > pH 8.4), also known as phenolsulfonphthalein and sulfophthalein, is a diagnostic aid for evaluating renal function. A typical stock indicator solution is 0.1 g phenol red in 28.2 mL 10 mM NaOH and 221.8 mL water. Target(s): aldehyde reductase; glutaminase; gglutamyl transpeptidase; glutathione S-transferase; 4- methyleneglutaminase; phosphate uptake; thromboxane A2/prostaglandin H2 receptor; and thyroglobulin iodination. |
Phenol Red Preparation Products And Raw materials
| Raw materials | Zinc chloride-->2-Sulfobenzoic anhydride-->L-Cysteine hydrochloride monohydrate |
| Preparation Products | Bromophenol Blue |
