PINOSYLVIN CAS 22139-77-1

Introduction：Basic information about PINOSYLVIN CAS 22139-77-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

PINOSYLVIN Basic information

• Product Name: PINOSYLVIN
• Synonyms: (e)-5-stilbenediol;5-(2-phenylethenyl)-3-benzenedio(e)-;pinosylvine;AKOS 211-07;3,5-DIHYDROXY-STILBENE;3,5-TRANS-DIHYDROXYSTILBENE;5-(2-Phenylethenyl)benzene-1,3-diol;5-[(E)-2-Phenylethenyl]-1,3-benzenediol
• CAS: 22139-77-1
• MF: C14H12O2
• MW: 212.24
• EINECS: 683-184-0
• Product Categories: Stilbenes (substituted)
• Mol File: 22139-77-1.mol

PINOSYLVIN Chemical Properties

• Melting point: 153-157 °C
• Boiling point: 312.08°C (rough estimate)
• density: 1.1035 (rough estimate)
• refractive index: 1.6000 (estimate)
• storage temp.: 2-8°C
• solubility: DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:50): 0.01mg/mL; DMSO: 10mg/mL; Ethanol: 20mg/mL; Ethanol:PBS (pH 7.2) (1:50): 0.01mg/mL
• form: A solid
• pka: 9.34±0.10(Predicted)
• color: White to off-white
• BRN: 1870942
• InChI: InChI=1S/C14H12O2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10,15-16H/b7-6+
• InChIKey: YCVPRTHEGLPYPB-VOTSOKGWSA-N
• SMILES: C1(O)=CC(/C=C/C2=CC=CC=C2)=CC(O)=C1
• LogP: 3.680 (est)

Safety Information

• Hazard Codes: Xn,N
• Risk Statements: 22-36-51/53
• Safety Statements: 26-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• RTECS: WJ5580000

PINOSYLVIN Usage And Synthesis

Chemical Properties

Off-white crystalline powder

Uses

Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility.

Definition

ChEBI: Pinosylvin is a stilbenol.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Enzyme inhibitor

This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. = 155.5-156°C; low solubility in water), also known as (E)-3,5-stilbenediol and trans-3,5-dihydroxystilbene and named systematically as 5-[(E)-2- phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine and other woody plants. Pinosylvin exxhibits micromolar Ki values for specific isozymes of stilbene synthase and chalcone synthase. Target(s): chalcone synthase; stilbene synthase; tyrosinase, or monophenol monooxygenase.