Procysteine CAS 19771-63-2

Introduction：Basic information about Procysteine CAS 19771-63-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Procysteine Basic information

• Product Name: Procysteine
• Synonyms: (4R)-2-Oxothiazolidine-4-carboxylic acid;(4R)-2-Oxothiazolidine-4α-carboxylic acid;L-2-Thiazolidinone-4-carboxylic Acid,L-2-Oxothiazolidine-4-carboxylic Acid;(4R)-2-ketothiazolidine-4-carboxylic acid;L-Thiazolidin-2-one-4-carboxylic acid, OTC, Procysteine, OTZ;Oxothiazolidine carboxylate;4-Thiazolidinecarboxylicacid, 2-oxo-, (4R)-;L-2-Thiazolidinone-4-carboxylic Acid
• CAS: 19771-63-2
• MF: C4H5NO3S
• MW: 147.15
• EINECS: 200-154-8
• Product Categories: CARBOXYLICACID;whitening and anti-aging material and other functions in cosmetics
• Mol File: 19771-63-2.mol

Procysteine Chemical Properties

• Melting point: 174 °C (dec.)(lit.)
• alpha: -60 º (c=1 in H2O)
• density: 1.582±0.06 g/cm3(Predicted)
• refractive index: -64 ° (C=1, H2O)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• pka: pKa (22°): 3.32
• form: Powder
• color: White to Off-white
• Water Solubility: Soluble in water
• Merck: 13,7019
• BRN: 4179169
• Cosmetics Ingredients Functions: SKIN CONDITIONING
• InChI: InChI=1S/C4H5NO3S/c6-3(7)2-1-9-4(8)5-2/h2H,1H2,(H,5,8)(H,6,7)/t2-/m0/s1
• InChIKey: BMLMGCPTLHPWPY-REOHCLBHSA-N
• SMILES: S1C[C@@H](C(O)=O)NC1=O
• CAS DataBase Reference: 19771-63-2(CAS DataBase Reference)

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: XJ5426650
• HS Code: 2934.20.8000
• Storage Class: 11 - Combustible Solids

Procysteine Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

(R)-(-)-2-Oxothiazolidine-4-carboxylic Acid or Procysteine is a precursor to glutathione (GSH) which is an important antioxidant in plants, animals and fungi.

Definition

ChEBI: (4R)-2-oxo-4-thiazolidinecarboxylic acid is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

Biological Activity

2-Oxothiazolidine-4-carboxylic acid augments glutathione and cysteine production.

in vivo

Oxothiazolidinecarboxylic acid treatment attenuates plantaris atrophy, restored glutathione levels, and increased catalase, Cu/Zn-SOD1, and Mn-SOD2 mRNA expression, but did not reduce other markers of oxidant stress or levels of these catabolic factors^[1].

• Animal Model: Male Sprague-Dawley rats (200-250 g, n= 6-7 rats/group)^[1].
• Dosage: 0.35% (w/v).
• Administration: Added to their diets at a concentration of 0.35% (w/v) for the final 12 wk.
• Result: Increased fiber CSAs compared to the non-supplemented, alcohol-fed group.