Introduction：Basic information about CAS 65189-64-2|(D-Ala2)-Leu-Enkephalin amide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (D-Ala2)-Leu-Enkephalin amide |
|---|
| CAS Number | 65189-64-2 | Molecular Weight | 568.66400 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C29H40N6O6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | (2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide |
|---|
| Synonym | More Synonyms |
|---|
(D-Ala2)-Leu-Enkephalin amide BiologicalActivity
| Description | [D-Ala2] Leu-Enkephalinamide is an enkephalin analog. [D-Ala2] Leu-Enkephalinamide has great corneal permeability and analgesic effect. [D-Ala2] Leu-Enkephalinamide can be used for the research of ocular diseases[1][2]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
|---|
| In Vitro | [D-Ala2] Leu-Enkephalinamide (MEA) (1.0 mM; 10-240 min) has great corneal permeability in vitro[1]. |
|---|
| In Vivo | D-Ala2-Leu-enkephalinamide (s.c.) is also enhanced in morphine-dependent animals[2]. |
|---|
Chemical & Physical Properties
| Molecular Formula | C29H40N6O6 |
|---|
| Molecular Weight | 568.66400 |
|---|
| Exact Mass | 568.30100 |
|---|
| PSA | 220.69000 |
|---|
| LogP | 4.83780 |
|---|
| InChIKey | YPERDMXQKOFCQT-JMBSJVKXSA-N |
|---|
| SMILES | CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(C)NC(=O)C(N)Cc1ccc(O)cc1)C(N)=O |
|---|
Synonyms
| Leu-enkephalinamide,ala(2) |
| enkephalinamide-Leu,Ala(2) |
| 2-Ala-leu-enkephalinamide |
| Enkephalinamide-leu,alanine(2) |
| DALEA |
| Leucine-enkephalinamide,ala(2) |
| DALE |
| (D-Ala2)-Leu-Enkephalin amide |
| Ala(2)-Enkephalinamide-Leu |
