CAS 635287-26-2|Fmoc-NH-PEG5-CH2COOH

Introduction:Basic information about CAS 635287-26-2|Fmoc-NH-PEG5-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameFmoc-NH-PEG5-CH2COOH
CAS Number635287-26-2Molecular Weight517.56800
Density/Boiling Point/
Molecular FormulaC27H35NO9Melting Point/
MSDS/Flash Point/

Names

Name{2-[2-(2-{2-[2-(9H-fluoren-9-yl-methoxycarbonylamino)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}acetic acid
SynonymMore Synonyms

Fmoc-NH-PEG5-CH2COOH BiologicalActivity

DescriptionFmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Liuhong CHEN, et al. Multimeric bicyclic peptide ligands. WO2019162682A1.

Chemical & Physical Properties

Molecular FormulaC27H35NO9
Molecular Weight517.56800
Exact Mass517.23100
PSA121.78000
LogP3.08360
InChIKeyLNIFRTLAPAPKAG-UHFFFAOYSA-N
SMILESO=C(O)COCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21
Storage condition2-8°C

Synonyms

Fmoc-NH-5(ethylene glycol)-acetic acid
FMOC-NH-DPEG5-COOH
Fmoc-NH-PEG5-CH2COOH
Fmoc-NH-5(ethylene glycol)-actic acid
5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
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