Introduction:Basic information about CAS 635287-26-2|Fmoc-NH-PEG5-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-NH-PEG5-CH2COOH |
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| CAS Number | 635287-26-2 | Molecular Weight | 517.56800 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C27H35NO9 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | {2-[2-(2-{2-[2-(9H-fluoren-9-yl-methoxycarbonylamino)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}acetic acid |
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| Synonym | More Synonyms |
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Fmoc-NH-PEG5-CH2COOH BiologicalActivity
| Description | Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Liuhong CHEN, et al. Multimeric bicyclic peptide ligands. WO2019162682A1. |
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Chemical & Physical Properties
| Molecular Formula | C27H35NO9 |
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| Molecular Weight | 517.56800 |
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| Exact Mass | 517.23100 |
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| PSA | 121.78000 |
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| LogP | 3.08360 |
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| InChIKey | LNIFRTLAPAPKAG-UHFFFAOYSA-N |
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| SMILES | O=C(O)COCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
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| Storage condition | 2-8°C |
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Synonyms
| Fmoc-NH-5(ethylene glycol)-acetic acid |
| FMOC-NH-DPEG5-COOH |
| Fmoc-NH-PEG5-CH2COOH |
| Fmoc-NH-5(ethylene glycol)-actic acid |
| 5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester |