Introduction:Basic information about CAS 97-05-2|Sulfosalicylic Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sulfosalicylic Acid |
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| CAS Number | 97-05-2 | Molecular Weight | 218.184 |
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| Density | 1.8±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C7H6O6S | Melting Point | 120°C |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-Sulfosalicylic acid |
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| Synonym | More Synonyms |
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Sulfosalicylic Acid BiologicalActivity
| Description | 5-Sulfosalicylic acid is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid is effective against the breast cancer cell line, MCF-7, with less toxicity[1]. 5-Sulfosalicylic acid has antioxidant activities[2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | 5-Sulfosalicylic acid (0.5-4 mM, 24 h) shows a reduction in the viability of MCF-7 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: MCF-7 and HUVEC cells Concentration: 0.5, 1, 2, 4 mM Incubation Time: 24 hours Result: Showed the viability of 63.3% and 70.4% in MCF-7 and HUVEC control cells respectively at 1 mM 5-Sulfosalicylic acid. |
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| References | [1]. Münteha Özsoy, et al. A protein-sulfosalicylic acid/boswellic acids @metal-organic framework nanocomposite as anticancer drug delivery system. Colloids Surf B Biointerfaces. 2021 Aug;204:111788. [2]. K. Ezhilmathi, et al. Effect of 5-sulfosalicylic acid on antioxidant activity in relation to vase life of Gladiolus cut flowers. Plant Growth Regul 51, 99 (2007). |
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Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
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| Melting Point | 120°C |
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| Molecular Formula | C7H6O6S |
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| Molecular Weight | 218.184 |
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| Exact Mass | 217.988510 |
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| PSA | 120.28000 |
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| LogP | -0.69 |
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| Index of Refraction | 1.650 |
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| InChIKey | YCPXWRQRBFJBPZ-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1cc(S(=O)(=O)O)ccc1O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VO6500000
- CHEMICAL NAME :
- Salicylic acid, 5-sulfo-
- CAS REGISTRY NUMBER :
- 97-05-2
- BEILSTEIN REFERENCE NO. :
- 0650741
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C7-H6-O6-S
- MOLECULAR WEIGHT :
- 218.19
- WISWESSER LINE NOTATION :
- WSQR DQ CVQ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1850 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570587
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,565,1969
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 7940 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570587 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81215 No. of Facilities: 2580 (estimated) No. of Industries: 7 No. of Occupations: 10 No. of Employees: 18777 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81215 No. of Facilities: 1425 (estimated) No. of Industries: 4 No. of Occupations: 16 No. of Employees: 44936 (estimated) No. of Female Employees: 36255 (estimated)
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Safety Information
| Hazard Codes | Xn |
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| Risk Phrases | R22;R36/37/38 |
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| Safety Phrases | S26 |
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| RIDADR | UN 1760 |
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| Packaging Group | III |
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| Hazard Class | 8 |
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| HS Code | 2918290000 |
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Customs
| HS Code | 2918290000 |
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| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| Sulfosalicylic Acid |
| 5-Sulfosalicylic Acid |
| EINECS 202-555-6 |
| MFCD00007508 |
| Benzoic acid, 2-hydroxy-5-sulfo- |
| Sulphosalicylic acid |
| 2-Hydroxy-5-sulfobenzoic acid |