CAS 58880-05-0|EMA [Ethidium monoazide bromide]

Introduction：Basic information about CAS 58880-05-0|EMA [Ethidium monoazide bromide], including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. EMA [Ethidium monoazide bromide] BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles41
7. Synonyms

Common Name	EMA [Ethidium monoazide bromide]
CAS Number	58880-05-0	Molecular Weight	420.30500
Density	/	Boiling Point	/
Molecular Formula	C₂₁H₁₈BrN₅	Melting Point	/
MSDS	ChineseUSA	Flash Point	/

Names

Name	8-azido-5-ethyl-6-phenylphenanthridin-5-ium-3-amine,bromide
Synonym	More Synonyms

EMA [Ethidium monoazide bromide] BiologicalActivity

Description	Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Nogva HK, et al. Ethidium monoazide for DNA-based differentiation of viable and dead bacteria by 5'-nuclease PCR. Biotechniques. 2003 Apr;34(4):804-8, 810, 812-3.

Chemical & Physical Properties

Molecular Formula	C₂₁H₁₈BrN₅
Molecular Weight	420.30500
Exact Mass	419.07500
PSA	79.65000
LogP	2.52936
InChIKey	GHUXAYLZEGLXDA-UHFFFAOYSA-N
SMILES	CC[n+]1c(-c2ccccc2)c2cc(N=[N+]=[N-])ccc2c2ccc(N)cc21.[Br-]

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SF7941850

CHEMICAL NAME :: Phenanthridinium, 3-amino-8-azido-5-ethyl-6-phenyl-, bromide

CAS REGISTRY NUMBER :: 58880-05-0

LAST UPDATED :: 199707

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C21-H18-N5.Br

MOLECULAR WEIGHT :: 420.35

WISWESSER LINE NOTATION :: T B666 HKJ EZ H2 IR& LNNN &E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 2 umol/L/30M

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 56,21,1977

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
RTECS	SF7941850

Articles41

Modified vaccinia virus Ankara-infected dendritic cells present CD4+ T-cell epitopes by endogenous major histocompatibility complex class II presentation pathways.

J. Virol. 89(5) , 2698-709, (2015)

CD4(+) T lymphocytes play a central role in the immune system and mediate their function after recognition of their respective antigens presented on major histocompatibility complex II (MHCII) molecul...

Propidium monoazide (PMA) and ethidium bromide monoazide (EMA) improve DNA array and high-throughput sequencing of porcine reproductive and respiratory syndrome virus identification.

J. Virol. Methods 222 , 182-91, (2015)

Pan-viral DNA array (PVDA) and high-throughput sequencing (HTS) are useful tools to identify novel viruses of emerging diseases. However, both techniques have difficulties to identify viruses in clini...

Extracellular matrices decellularized from embryonic stem cells maintained their structure and signaling specificity.

Tissue Eng. Part A 20(1-2) , 54-66, (2014)

Embryonic stem cells (ESCs) emerge as a promising tool for tissue engineering and regenerative medicines due to their extensive self-renewal ability and the capacity to give rise to cells from all thr...

Synonyms

Phenanthridinium,3-amino-8-azido-5-ethyl-6-phenyl-,bromide

MFCD00213986

3-Amino-8-azido-5-ethyl-6-phenylphenanthridinium bromide

Ethidium azide bromide

Ethidium bromide monoazide

Ethidium monoazide bromide

Monoazido ethidium bromide

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