CAS 64724-75-0|Oxonol VI

Introduction：Basic information about CAS 64724-75-0|Oxonol VI, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Oxonol VI BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles26
6. Synonyms

Common Name	Oxonol VI
CAS Number	64724-75-0	Molecular Weight	316.35200
Density	1.19g/cm3	Boiling Point	381.4ºC at 760 mmHg
Molecular Formula	C₁₇H₂₀N₂O₄	Melting Point	/
MSDS	ChineseUSA	Flash Point	184.5ºC

Names

Name	(4Z)-4-[(2E,4E)-5-(5-oxo-3-propyl-2H-1,2-oxazol-4-yl)penta-2,4-dienylidene]-3-propyl-1,2-oxazol-5-one
Synonym	More Synonyms

Oxonol VI BiologicalActivity

Description	Oxonol VI acts as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is suitable for detecting changes of membrane potential associated with the activity of the (Na+ + K+)-ATPase in reconstituted vesicles[1].
Related Catalog	Research Areas >>Neurological Disease
References	[1]. H J Apell, et al. Oxonol VI as an optical indicator for membrane potentials in lipid vesicles. Biochim Biophys Acta. 1987 Oct 16;903(3):480-94.

Chemical & Physical Properties

Density	1.19g/cm3
Boiling Point	381.4ºC at 760 mmHg
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.35200
Flash Point	184.5ºC
Exact Mass	316.14200
PSA	84.92000
LogP	2.97700
Index of Refraction	1.563
InChIKey	SBJHIADVIBJMQL-PQWGHOHWSA-N
SMILES	CCCC1=NOC(=O)C1=CC=CC=Cc1c(CCC)[nH]oc1=O

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport

Articles26

Conserved amino acid residues of the NuoD segment important for structure and function of Escherichia coli NDH-1 (complex I).

Biochemistry 54(3) , 753-64, (2015)

The NuoD segment (homologue of mitochondrial 49 kDa subunit) of the proton-translocating NADH:quinone oxidoreductase (complex I/NDH-1) from Escherichia coli is in the hydrophilic domain and bears many...

ATP-dependent spectral response of oxonol VI in an ATP-Pi exchange complex.

Biochim. Biophys. Acta 766(2) , 375-85, (1984)

Energy transduction in an ATPase complex (complex V) has been studied in two reactions catalyzed by this system, i.e., ATP-dependent spectral shift of oxonol VI, and ATP-Pi exchange activity. Aurovert...

Effects of Cd2+ on ATP-driven membrane potential in beef heart mitochondrial H+-ATPase: a study using the voltage-sensitive probe oxonol VI.

Membr. Biochem. 5(3) , 225-41, (1984)

Beef heart mitochondrial H+-ATPase (F1-F0) vesicles were prepared by lysolecithin extraction of ETPH. ATP-driven membrane potential was monitored indirectly by following absorbance changes of the pote...

Synonyms

oxonol VI

Bis(3-propyl-5-oxoisoxazol-4-yl)pentamethine oxanol

MFCD00210076

5(4H)-Isoxazolone,4-(5-(5-hydroxy-3-propyl-4-isoxazolyl)-2,4-pentadienylidene)-3-propyl

Oxanol VI

Bis(3-propyl-5-oxoisoxazol-4-yl)pentamethineoxonol

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