CAS 2887-91-4|nordoxepin
Introduction：Basic information about CAS 2887-91-4|nordoxepin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | nordoxepin | ||
|---|---|---|---|
| CAS Number | 2887-91-4 | Molecular Weight | 265.350 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 420.8±44.0 °C at 760 mmHg |
| Molecular Formula | C18H20ClNO | Melting Point | 159-160ºC |
| MSDS | ChineseUSA | Flash Point | 174.5±17.9 °C |
| Symbol | GHS07, GHS09 | Signal Word | Warning |
Names
| Name | Nordoxepin Hydrochloride |
|---|---|
| Synonym | More Synonyms |
nordoxepin BiologicalActivity
| Description | Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the treatment of mild depression[1]. |
|---|---|
| Related Catalog | Research Areas >>Neurological Disease |
| References | [1]. Negrusz A, et al. Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapy. J Anal Toxicol. 1998;22(6):531-536. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 420.8±44.0 °C at 760 mmHg |
| Melting Point | 159-160ºC |
| Molecular Formula | C18H20ClNO |
| Molecular Weight | 265.350 |
| Flash Point | 174.5±17.9 °C |
| Exact Mass | 265.146667 |
| PSA | 21.26000 |
| LogP | 4.59 |
| Appearance of Characters | powder | white to off-white |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.635 |
| InChIKey | GNPPEZGJRSOKRE-UHFFFAOYSA-N |
| SMILES | CNCCC=C1c2ccccc2COc2ccccc21.Cl |
| Storage condition | -20°C Freezer |
Safety Information
| Symbol | GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H400 |
| Precautionary Statements | P273 |
| Hazard Codes | Xn,N |
| Risk Phrases | 22-50/53 |
| Safety Phrases | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
Articles26
More Articles| Determination of perhexiline and its metabolite hydroxyperhexiline in human plasma by liquid chromatography/tandem mass spectrometry. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(27) , 3025-30, (2009) Perhexiline is a drug that is used for treatment of moderate to severe angina pectoris that has not responded to other treatment. It has a low therapeutic index, and saturable metabolism that is also ... | |
| Simultaneous determination of doxepin and nordoxepin in serum using high-performance liquid chromatography. J. Chromatogr. A. 419 , 445-51, (1987) | |
| Quantitative determination of E- and Z-doxepin and E- and Z-desmethyldoxepin by high-performance liquid chromatography. Ther. Drug Monit. 17(4) , 371-6, (1995) A high-performance liquid chromatographic (HPLC) method was developed for the quantitative, simultaneous determination of the following four compounds in serum: E-doxepin, Z-doxepin, E-desmethyldoxepi... |
Synonyms
| (3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methylpropan-1-amine |
| 3-Dibenz(b,e)oxepin-11(6H)-ylidene-N-methyl-1-propanamine |
| 1-Propanamine,3-dibenzb,eoxepin-11(6H)-ylidene-N-methyl-,hydrochloride |
| 11[6H]-[3-(METHYLAMINO)PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE |
| nordoxepin |
| N-DesMethyldoxepin-d3 Hydrochloride |
| 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-, (3Z)- |
| 11(6h)-(3-[methylamino]propylidene)dibenz[b,e]oxepine |
| 1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N-methyl- |
| NorDoxepinHydrochloride |
| (3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methyl-1-propanamine |
| 3-Dibenzo[b,e]oxepin-11(6H)-ylidene-N-methylpropan-1-amine |
| demethyldoxepin |
| 3-(Dibenz[b,e]oxepin-11(6H)-ylidene)-N-Methyl |
| N-Desmethyldoxepin |
| N-DesMethyldoxepin Hydrochloride |
