CAS 497-30-3|L-(+)-Ergothioneine
| Common Name | L-(+)-Ergothioneine | ||
|---|---|---|---|
| CAS Number | 497-30-3 | Molecular Weight | 229.299 |
| Density | / | Boiling Point | / |
| Molecular Formula | C9H15N3O2S | Melting Point | 275-277ºC (dec.) |
| MSDS | USA | Flash Point | / |
Names
| Name | ergothioneine |
|---|---|
| Synonym | More Synonyms |
L-(+)-Ergothioneine BiologicalActivity
| Description | Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Oumari M, et al. Regeneration of ergothioneine after reaction with singlet oxygen. Free Radic Biol Med. 2019 Apr;134:498-504. |
Chemical & Physical Properties
| Melting Point | 275-277ºC (dec.) |
|---|---|
| Molecular Formula | C9H15N3O2S |
| Molecular Weight | 229.299 |
| Exact Mass | 229.088501 |
| PSA | 100.97000 |
| LogP | -3.43 |
| InChIKey | SSISHJJTAXXQAX-ZETCQYMHSA-N |
| SMILES | C[N+](C)(C)C(Cc1c[nH]c(=S)[nH]1)C(=O)[O-] |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles43
More Articles| Effect of mushroom diet on pharmacokinetics of gabapentin in healthy Chinese subjects. Br. J. Clin. Pharmacol. 78(1) , 129-34, (2014) This study evaluated the pharmacokinetics of gabapentin in Chinese subjects who received a diet rich in shiitake mushrooms. Shiitake mushrooms have been shown to contain high amount of ergothioneine. ... | |
| The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis. Eukaryotic Cell 11(10) , 1226-38, (2012) The function of a number of genes in the gliotoxin biosynthetic cluster (gli) in Aspergillus fumigatus remains unknown. Here, we demonstrate that gliK deletion from two strains of A. fumigatus complet... | |
| Uptake and protective effects of ergothioneine in human endothelial cells. J. Pharmacol. Exp. Ther. 350(3) , 691-700, (2014) Ergothioneine is a thiourea derivative of histidine found in food, especially mushrooms. Experiments in cell-free systems and chemical assays identified this compound as a powerful antioxidant. Experi... |
Synonyms
| ergothioneine |
| L-Ergothioneine |
| (2S)-3-(2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)-2-(trimethylammonio)propanoate |
| [(S)-1-carboxy-2-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-ethyl]-trimethyl-ammonium,betaine |
| Thiolhistidine betaine |
| Sympectothion |
| (S)-a-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium Hydroxide Inner Salt |
| L(+)-Ergothioneine |
| Thiotane |
| 2-thiol-L-histidine-betaine |
| 1H-Imidazole-4-ethanaminium, α-carboxy-2-mercapto-N,N,N-trimethyl-, inner salt, (αS)- |
| [(S)-1-Carboxy-2-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-aethyl]-trimethyl-ammonium,Betain |
| Ammonium, [1-carboxy-2-(2-thioxo-4-imidazolin-4-yl)ethyl]trimethyl-, hydroxide, inner salt |
| (2S)-3-(2-Sulfanyl-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate |
| [1-Carboxy-2-[2-mercaptoimidazol-4(or 5)-yl]ethyl]trimethylammonium Hydroxide Inner Salt |
| thiotaine |
| Thiasine |
| 1H-imidazole-5-ethanaminium, α-carboxy-2-mercapto-N,N,N-trimethyl-, inner salt, (αS)- |
| Thiolhistidine-βine |
| Phytothioneine |
