CAS 509-18-2|Delsoline

Introduction：Basic information about CAS 509-18-2|Delsoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Delsoline BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	Delsoline
CAS Number	509-18-2	Molecular Weight	467.595
Density	1.3±0.1 g/cm3	Boiling Point	576.0±50.0 °C at 760 mmHg
Molecular Formula	C₂₅H₄₁NO₇	Melting Point	214ºC
MSDS	/	Flash Point	302.1±30.1 °C

Names

Name	(1α,6β,8ξ,14α,16β,17R)-20-Ethyl-6,14,16-trimethoxy-4-(methoxymeth yl)aconitane-1,7,8-triol
Synonym	More Synonyms

Delsoline BiologicalActivity

Description	Delsoline, a major alkaloid of Delphinium anthriscifolium Hance, has both a curare-like effect and a ganglion-blocking effect and is used to relieve muscle tension or hyperkinesia. D. anthriscifolium Hance has effects of dispelling wind and dampness, activating collaterals, and relieving pains and is used to treat rheumatism, hemiplegia, indigestion, and cough[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic DiseaseResearch Areas >>Neurological Disease
References	[1]. Shao L, et al. Pharmacokinetics and UPLC-MS/MS of Delsoline in Mouse Whole Blood. J Anal Methods Chem. 2018 Oct 11;2018:9412708.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	576.0±50.0 °C at 760 mmHg
Melting Point	214ºC
Molecular Formula	C₂₅H₄₁NO₇
Molecular Weight	467.595
Flash Point	302.1±30.1 °C
Exact Mass	467.288300
PSA	100.85000
LogP	-0.27
Vapour Pressure	0.0±3.6 mmHg at 25°C
Index of Refraction	1.596
InChIKey	JVBLTQQBEQQLEV-UHFFFAOYSA-N
SMILES	CCN1CC2(COC)CCC(O)C34C5CC6C(OC)CC(O)(C5C6OC)C(O)(C(OC)C23)C14
Storage condition	2-8C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR5569490

CHEMICAL NAME :: Aconitane-1,7,8-triol, 20-ethyl-4-(methoxymethyl)-6,14,16-trimethoxy-, (1-alpha,6-beta,14-alpha,16-beta)-

CAS REGISTRY NUMBER :: 509-18-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C25-H41-N-O7

MOLECULAR WEIGHT :: 467.67

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981

Safety Information

RTECS	AR5569490

Synonyms

Xuan-Wu 3

Bullatine-B

Dideacetyldelphisine

20-Ethyl-6,16-dimethoxy-4-(methoxymethyl)aconitane-1,8,14-triol

Delsoline

(1α,6β,14α,16β)-20-Ethyl-6,14,16-trimethoxy-4-(methoxymethyl)aconitane-1,7,8-triol

Aconitane-1,7,8-triol, 20-ethyl-6,14,16-trimethoxy-4-(methoxymethyl)-, (1α,6β,14α,16β)-

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