CAS 473382-39-7|Akt-l-1

Introduction：Basic information about CAS 473382-39-7|Akt-l-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Akt-l-1 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Akt-l-1
CAS Number	473382-39-7	Molecular Weight	378.514
Density	1.2±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₂₂H₃₀N₆	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	N-(7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N',N',2,2-tetramethylpropane-1,3-diamine
Synonym	More Synonyms

Akt-l-1 BiologicalActivity

Description	AKT-I-1 is a selective inhibitor of Akt1, with an IC50 of 4.6 µM[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PI3K/Akt/mTOR >>Akt
Target	Akt1:4.6 μM (IC50) Akt2:>250 μM (IC50) Akt3:>250 μM (IC50)
References	[1]. Barnett SF, et al. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors. Biochem J. 2005 Jan 15;385(Pt 2):399-408.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Molecular Formula	C₂₂H₃₀N₆
Molecular Weight	378.514
Exact Mass	378.253204
PSA	61.58000
LogP	4.01
Index of Refraction	1.642
InChIKey	FKCXKEHHZXEWGP-UHFFFAOYSA-N
SMILES	CN(C)CC(C)(C)CNc1nn2c(-c3ccccc3)nnc2cc1C1CCC1

Synonyms

1,3-Propanediamine, N-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N,N,2,2-tetramethyl-

Akt-l-1

N'-(7-Cyclobutyl-3-phenyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N,N,2,2-tetramethyl-1,3-propanediamine

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