Introduction：Basic information about CAS 475231-21-1|3'-Hydroxypterostilbene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3'-Hydroxypterostilbene |
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| CAS Number | 475231-21-1 | Molecular Weight | 272.296 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 469.7±45.0 °C at 760 mmHg |
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| Molecular Formula | C16H16O4 | Melting Point | / |
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| MSDS | / | Flash Point | 237.8±28.7 °C |
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Names
| Name | 3'-Hydroxypterostilbene |
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| Synonym | More Synonyms |
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3'-Hydroxypterostilbene BiologicalActivity
| Description | 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerSignaling Pathways >>Autophagy >>Autophagy |
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| Target | Apoptosis[1] Autophagy[1] |
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| References | [1]. Cheng TC, et al. Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors. PLoS One. 2014 Nov 12;9(11):e111814. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 469.7±45.0 °C at 760 mmHg |
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| Molecular Formula | C16H16O4 |
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| Molecular Weight | 272.296 |
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| Flash Point | 237.8±28.7 °C |
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| Exact Mass | 272.104858 |
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| PSA | 58.92000 |
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| LogP | 3.68 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.665 |
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| InChIKey | UQRBFXIUUDJHSN-ONEGZZNKSA-N |
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| SMILES | COc1cc(C=Cc2ccc(O)c(O)c2)cc(OC)c1 |
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| Storage condition | -20℃ |
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Synonyms
| 1,2-Benzenediol, 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]- |
| 4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]-1,2-benzenediol |
| 4-[2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol |
| 4-(2-(3,5-dimethoxyphenyl)ethenyl)-1,2-benzenediol |
| 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol |
| 4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol |
| (E)-4-(3,5-Dimethoxystyryl)benzene-1,2-diol |
