Introduction：Basic information about CAS 490-83-5|L-Dehydroascorbic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-Dehydroascorbic acid |
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| CAS Number | 490-83-5 | Molecular Weight | 174.108 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 389.3±38.0 °C at 760 mmHg |
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| Molecular Formula | C6H6O6 | Melting Point | 228 °C (dec.)(lit.) |
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| MSDS | / | Flash Point | 170.0±20.3 °C |
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Names
| Name | dehydroascorbic acid |
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| Synonym | More Synonyms |
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L-Dehydroascorbic acid BiologicalActivity
| Description | Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. |
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| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Neurological Disease |
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| Target | Human Endogenous Metabolite |
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| In Vitro | Neuronal injury in ischemic stroke is partly mediated by cytotoxic reactive oxygen species. Although the antioxidant ascorbic acid (AA) or vitamin C does not penetrate the blood-brain barrier (BBB), its oxidized form, dehydroascorbic acid (DHA), enters the brain by means of facilitative transport[1]. |
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| References | [1]. Huang J, et al. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potentcerebroprotection in experimental stroke. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 389.3±38.0 °C at 760 mmHg |
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| Melting Point | 228 °C (dec.)(lit.) |
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| Molecular Formula | C6H6O6 |
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| Molecular Weight | 174.108 |
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| Flash Point | 170.0±20.3 °C |
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| Exact Mass | 174.016434 |
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| PSA | 100.90000 |
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| LogP | -2.32 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.570 |
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| InChIKey | SBJKKFFYIZUCET-JLAZNSOCSA-N |
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| SMILES | O=C1OC(C(O)CO)C(=O)C1=O |
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| Storage condition | −20°C |
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Safety Information
| Hazard Codes | Xn |
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| Risk Phrases | 22 |
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| WGK Germany | 3 |
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Synonyms
| L-threo-2,3-Hexodiulosonic Acid g-Lactone |
| (5R)-5-[(1S)-1,2-Dihydroxyethyl]-2,3,4(5H)-furantrion |
| MFCD00066467 |
| (5R)-5-[(1S)-1,2-Dihydroxyethyl]-2,3,4(5H)-furantrione |
| L-Dehydro Ascorbic Acid |
| DEHYDROASCORBIC ACID |
| EINECS 207-720-6 |
| L-Dehydroascorbic acid |
| L-threo-2,3-Hexodiulosonic acid γ-lactone |
| (5R)-5-[(1S)-1,2-Dihydroxyéthyl]-2,3,4(5H)-furanetrione |
| (5R)-5-[(1S)-1,2-Dihydroxyethyl]furan-2,3,4(5H)-trione (non-preferred name) |
