Introduction:Basic information about CAS 6377-18-0|Chartreusin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Chartreusin |
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| CAS Number | 6377-18-0 | Molecular Weight | 640.58800 |
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| Density | 1.63g/cm3 | Boiling Point | 945.5ºC at 760 mmHg |
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| Molecular Formula | C32H32O14 | Melting Point | / |
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| MSDS | / | Flash Point | 307.8ºC |
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Names
| Name | lambdamycin |
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| Synonym | More Synonyms |
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Chartreusin BiologicalActivity
| Description | Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Leach B E, et al. Chartreusin, a new antibiotic produced by Streptomyces chartreusis, a new species. Journal of the American Chemical Society, 1953, 75(16): 4011-4012. |
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Chemical & Physical Properties
| Density | 1.63g/cm3 |
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| Boiling Point | 945.5ºC at 760 mmHg |
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| Molecular Formula | C32H32O14 |
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| Molecular Weight | 640.58800 |
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| Flash Point | 307.8ºC |
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| Exact Mass | 640.17900 |
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| PSA | 207.72000 |
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| LogP | 1.36980 |
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| Index of Refraction | 1.718 |
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| InChIKey | PONPPNYZKHNPKZ-RYBWXQSLSA-N |
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| SMILES | COC1C(O)C(C)OC(OC2C(Oc3cccc4c(O)c5c(=O)oc6ccc(C)c7c(=O)oc(c34)c5c67)OC(C)C(O)C2O)C1O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- FL7350000
- CHEMICAL NAME :
- Chartreusin
- CAS REGISTRY NUMBER :
- 6377-18-0
- BEILSTEIN REFERENCE NO. :
- 0075649
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C32-H32-O14
- MOLECULAR WEIGHT :
- 640.64
- WISWESSER LINE NOTATION :
- T B66 K666 2AB T HVO SVOJ F1 QQ LO- BT6OTJ DQ EQ F1 CO- BT6OTJ CQ DO1 EQ F1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 34,173,1981
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Synonyms
| CHARTREUSIN |
| antibioticx-465a |
| u-7257 |
| chartreusin from streptomyces*chartreusis |