Introduction：Basic information about CAS 82-98-4|Piperidolate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Piperidolate |
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| CAS Number | 82-98-4 | Molecular Weight | 323.429 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 431.9±45.0 °C at 760 mmHg |
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| Molecular Formula | C21H25NO2 | Melting Point | / |
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| MSDS | / | Flash Point | 136.0±19.6 °C |
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Names
| Name | (1-ethylpiperidin-3-yl) 2,2-diphenylacetate |
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| Synonym | More Synonyms |
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Piperidolate BiologicalActivity
| Description | Piperidolate is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs). |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mAChRSignaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>Neurological Disease |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 431.9±45.0 °C at 760 mmHg |
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| Molecular Formula | C21H25NO2 |
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| Molecular Weight | 323.429 |
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| Flash Point | 136.0±19.6 °C |
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| Exact Mass | 323.188538 |
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| PSA | 29.54000 |
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| LogP | 4.44 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.584 |
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| InChIKey | KTHVBAZBLKXIHZ-UHFFFAOYSA-N |
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| SMILES | CCN1CCCC(OC(=O)C(c2ccccc2)c2ccccc2)C1 |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AH2900000
- CHEMICAL NAME :
- Acetic acid, diphenyl-, 1-ethyl-3-piperidyl ester
- CAS REGISTRY NUMBER :
- 82-98-4
- BEILSTEIN REFERENCE NO. :
- 0031110
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C21-H25-N-O2
- MOLECULAR WEIGHT :
- 323.47
- WISWESSER LINE NOTATION :
- T6NTJ A2 COVYR&R
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intradermal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 59,149,1938
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 16 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2933399090 |
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Customs
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Piperidolatum [INN-Latin] |
| Piperidolato [INN-Spanish] |
| 1-Ethyl-3-piperidinyl diphenylacetate |
| Diphenylessigsaeure-(1-aethyl-piperidin-3-yl-ester) |
| Diphenylacetic Acid 1-Ethyl-3-piperidyl Ester |
| Diphenylessigsaeure-(1-ethyl-piperidin-3-yl-ester) |
| JB 305 |
| diphenylacetic acid-(1-ethyl-[3]piperidyl ester) |
| EINECS 201-449-7 |
| a-Phenylbenzeneacetic Acid 1-Ethyl-3-piperidinyl Ester |
| Benzeneacetic acid, α-phenyl-, 1-ethyl-3-piperidinyl ester |
| 1-Ethyl-3-piperidyl diphenylacetate |
| Piperidolate |
| 1-Aethyl-3-benzhydrylcarbonyloxy-piperidin |
| Piperidolate [INN:BAN] |
| Benzeneacetic acid, α-phenyl-, 1-ethyl-3-piperidinyl ester (9CI) |
| N-Ethyl-3-piperidyl diphenylacetate |
| Diphenylessigsaeure-(1-aethyl-[3]piperidylester) |
| Dactil |
