CAS 79-36-7|Dichloroacetyl chloride
Introduction：Basic information about CAS 79-36-7|Dichloroacetyl chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dichloroacetyl chloride | ||
|---|---|---|---|
| CAS Number | 79-36-7 | Molecular Weight | 147.388 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 107.5±0.0 °C at 760 mmHg |
| Molecular Formula | C2HCl3O | Melting Point | < 25ºC |
| MSDS | ChineseUSA | Flash Point | 31.8±22.3 °C |
| Symbol | GHS05, GHS09 | Signal Word | Danger |
Names
| Name | dichloroacetyl chloride |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 107.5±0.0 °C at 760 mmHg |
| Melting Point | < 25ºC |
| Molecular Formula | C2HCl3O |
| Molecular Weight | 147.388 |
| Flash Point | 31.8±22.3 °C |
| Exact Mass | 145.909302 |
| PSA | 17.07000 |
| LogP | 1.27 |
| Vapour Pressure | 27.0±0.2 mmHg at 25°C |
| Index of Refraction | 1.467 |
| InChIKey | FBCCMZVIWNDFMO-UHFFFAOYSA-N |
| SMILES | O=C(Cl)C(Cl)Cl |
| Stability | Stable. Combustible. Incompatible with water, alcohols and oxidizing agents. Fumes in air. |
| Water Solubility | MAY DECOMPOSE |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2460 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2000 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 650 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 mg/kg/80W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19(Suppl 21),2,1992
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19(Suppl 21),2,1992
Safety Information
| Symbol | GHS05, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314-H400 |
| Precautionary Statements | P273-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive;N:Dangerousfortheenvironment; |
| Risk Phrases | R35;R50 |
| Safety Phrases | S9-S26-S45-S61 |
| RIDADR | UN 1765 8/PG 2 |
| WGK Germany | 2 |
| RTECS | AO6650000 |
| Packaging Group | II |
| Hazard Class | 8 |
Articles7
More Articles| Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity. Bioorg. Med. Chem. 16 , 5720-32, (2008) The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper desc... | |
| Autoimmune response in MRL+/+ mice following treatment with dichloroacetyl chloride or dichloroacetic anhydride. Toxicol. Appl. Pharmacol. 216(2) , 248-55, (2006) Dichloroacetyl chloride (DCAC) is formed from trichloroethene (TCE), which is implicated in inducing/accelerating autoimmune response. Due to its potent acylating activity, DCAC may convert proteins t... | |
| Photocatalysis of gaseous trichloroethylene (TCE) over TiO2: the effect of oxygen and relative humidity on the generation of dichloroacetyl chloride (DCAC) and phosgene. J. Hazard. Mater. 146(1-2) , 302-8, (2007) Batch photocatalytic degradation of 80+/-2.5 ppm V trichloroethylene (TCE) was conducted to investigate the effect of the oxygen and relative humidity (RH) on the formation of the dichloroacetyl chlor... |
Synonyms
| Acetyl chloride, 2,2-dichloro- |
| Dichloroacetyl chloride |
| 2,2-Dichloroacetyl chloride |
| EINECS 201-199-9 |
| MFCD00000840 |
