CAS 33396-29-1|Erythromycin A Enol Ether
| Common Name | Erythromycin A Enol Ether | ||
|---|---|---|---|
| CAS Number | 33396-29-1 | Molecular Weight | 715.91100 |
| Density | 1.2g/cm3 | Boiling Point | 791.6ºC at 760mmHg |
| Molecular Formula | C37H65NO12 | Melting Point | 133-135ºC |
| MSDS | USA | Flash Point | 432.6ºC |
Names
| Name | Erythromycin A Enol Ether |
|---|---|
| Synonym | More Synonyms |
Erythromycin A Enol Ether BiologicalActivity
| Description | Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
| References | [1]. A Deubel, et al. Development of an enhanced separation of erythromycin and its related substances by liquid chromatography. J Pharm Biomed Anal. 2007 Jan 17;43(2):493-8. [2]. Abdolreza Hassanzadeh, et al. Mechanism for the degradation of erythromycin A and erythromycin A 2'-ethyl succinate in acidic aqueous solution. J Phys Chem A. 2007 Oct 11;111(40):10098-104. |
Chemical & Physical Properties
| Density | 1.2g/cm3 |
|---|---|
| Boiling Point | 791.6ºC at 760mmHg |
| Melting Point | 133-135ºC |
| Molecular Formula | C37H65NO12 |
| Molecular Weight | 715.91100 |
| Flash Point | 432.6ºC |
| Exact Mass | 715.45100 |
| PSA | 165.84000 |
| LogP | 2.89230 |
| Index of Refraction | 1.542 |
| InChIKey | JFVYXJKGJMUGRG-KJPZRSJGSA-N |
| SMILES | CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C2(C)CC(C)=C(O2)C(C)C(O)C1(C)O |
| Storage condition | -20°C Freezer |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles25
More Articles| Sensitive high-performance liquid chromatographic determination of EM523, a new erythromycin derivative, in human plasma and urine with ultraviolet detection using column switching. J. Chromatogr. A. 616(1) , 144-50, (1993) A sensitive high-performance liquid chromatographic (HPLC) method using column switching is described for the determination of EM523 (I), a new erythromycin derivative, in human plasma and urine. The ... | |
| Comparison of the motor-stimulating action of EM523, an erythromycin derivative, and prostaglandin F2 alpha in conscious dogs. Jpn. J. Pharmacol. 63(2) , 209-17, (1993) The effect of EM523 [de(N-methyl)-N-ethyl-8,9-anhydroerythromycin A 6,9-hemiacetal], an erythromycin derivative, on gastrointestinal motility was investigated using conscious dogs in the fasting state... | |
| EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion. Peptides 17(6) , 895-900, (1996) We investigated the efficacy and the mechanism of action of EM523L, a nonpeptide motilin agonist (motilide), on the stimulation of gastric emptying and on the release of gut peptides after ingestion o... |
Synonyms
| 9-Deoxo-6-deoxy-6,9-epoxy-8,9-didehydroerythromycin |
| 8,9-anhydroerythromycin A 6,9-hemiacetal |
| 6,9-Epoxy-8,9-didehydro-9-deoxo-6-deoxyerythromycin |
| 8,9-anhydroerythromycin A 6,9-hemiketal |
| erythromycin hemiketal |
| 8,9-anhydroerythromycin 6,9-hemiketal |
| 6-Deoxy-9-deoxo-8,9-didehydro-6,9-epoxyerythromycin |
| 8,9-anhydroerythromycin A |
| EM 523 |
| Erythromycin Impurity 5 |
