CAS 343-94-2|2-(1h-indol-3-yl)ethanaminhydrochlorid

CHEMICAL IDENTIFICATION

RTECS NUMBER :

NL4375000

CHEMICAL NAME :

Indole, 3-(2-aminoethyl)-, monohydrochloride

CAS REGISTRY NUMBER :

343-94-2

LAST UPDATED :

199701

DATA ITEMS CITED :

7

MOLECULAR FORMULA :

C10-H12-N2.Cl-H

MOLECULAR WEIGHT :

196.70

WISWESSER LINE NOTATION :

T56 BMJ D2Z &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1300 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPMRAB Japanese Journal of Medical Sciences, Part 4: Pharmacology. (Tokyo, Japan) V.1-16, 1926-43. For publisher information, see JJPAAZ. Volume(issue)/page/year: 2,77,1927

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

197 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1620,1974

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

504 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 33,180,1970

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

109 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 23,43,1964

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

1 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPMRAB Japanese Journal of Medical Sciences, Part 4: Pharmacology. (Tokyo, Japan) V.1-16, 1926-43. For publisher information, see JJPAAZ. Volume(issue)/page/year: 2,77,1927 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4652 No. of Facilities: 10 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 34 (estimated) No. of Female Employees: 3 (estimated)

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