CAS 1896-62-4|trans-4-phenylbut-3-en-2-one
| Common Name | trans-4-phenylbut-3-en-2-one | ||
|---|---|---|---|
| CAS Number | 1896-62-4 | Molecular Weight | 146.186 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 260.8±9.0 °C at 760 mmHg |
| Molecular Formula | C10H10O | Melting Point | 38.5-41ºC |
| MSDS | ChineseUSA | Flash Point | 65.6±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | trans-benzylideneacetone |
|---|---|
| Synonym | More Synonyms |
trans-4-phenylbut-3-en-2-one BiologicalActivity
| Description | trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>PhospholipaseResearch Areas >>Inflammation/Immunology |
| Target | PLA2 |
| In Vitro | Benzylideneacetone (trans-Benzylideneacetone; 0.005, 0.05, 0.5, 5, 50, 500, 5000 μM) inhibits hemocytespreading behavior of hemocytes of S. exigua larvae. Benzylideneacetone enhances virulence of Bacillus thuringiensisagainst beet armyworm[1]. |
| References | [1]. Kwon B, et al. Benzylideneacetone, an immunosuppressant, enhances virulence of Bacillus thuringiensisagainst beet armyworm (Lepidoptera: Noctuidae). J Econ Entomol. 2008 Feb;101(1):36-41. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 260.8±9.0 °C at 760 mmHg |
| Melting Point | 38.5-41ºC |
| Molecular Formula | C10H10O |
| Molecular Weight | 146.186 |
| Flash Point | 65.6±0.0 °C |
| Exact Mass | 146.073166 |
| PSA | 17.07000 |
| LogP | 2.17 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.563 |
| InChIKey | BWHOZHOGCMHOBV-BQYQJAHWSA-N |
| SMILES | CC(=O)C=Cc1ccccc1 |
| Water Solubility | practically insoluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 300 ug/plate
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,427,1982
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 300 ug/plate
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,427,1982
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H317-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | EN0330050 |
| HS Code | 2914399090 |
Customs
| HS Code | 2914399090 |
|---|---|
| Summary | 2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Synonyms
| Benzylideneacetone |
| benzylidene-2,4,6-trimethylacetophenone |
| Benzal-3-nitroaniline |
| trans-4-Phenyl-3-buten-2-one |
| (E)-4-Phenyl-3-buten-2-one |
| 2',4',6'-Trimethyl-chalkon |
| N-benzylidene-3-nitro-aniline |
| Benzal-m-nitroaniline |
| mesityl styryl ketone |
| PhCH=NC6H4-NO2-m |
| EINECS 204-555-1 |
| ANILINE,N-BENZYLIDENE-m-NITRO |
| 4-phenylbut-3-en-2-one |
| Benzylidene acetone |
| 2',4',6'-trimethyl-chalcone |
| 3-Buten-2-one, 4-phenyl- |
| benzalacetomesitylene |
| MFCD00008779 |
| 4-Phenyl-3-buten-2-one |
| N-Benzylidene-m-nitroaniline |
| WLN: WNR CNU1R |
| (E)-4-Phenylbut-3-en-2-one |
| trans-Benzylidenacetone |
| N-Benzyliden-3-nitro-anilin |
