CAS 64118-39-4|dodecanoic-2,2-d2 acid

Introduction：Basic information about CAS 64118-39-4|dodecanoic-2,2-d2 acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. dodecanoic-2,2-d2 acid BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	dodecanoic-2,2-d2 acid
CAS Number	64118-39-4	Molecular Weight	202.33
Density	/	Boiling Point	225ºC100 mm Hg(lit.)
Molecular Formula	C₁₂H₂₂D₂O₂	Melting Point	44-46ºC(lit.)
MSDS	USA	Flash Point	113ºC

Names

Name	2,2-dideuteriododecanoic acid
Synonym	More Synonyms

dodecanoic-2,2-d2 acid BiologicalActivity

Description	Lauric acid-d2 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
Related Catalog	Signaling Pathways >>Anti-infection >>Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Nakatsuji T, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol. 2009 Oct;129(10):2480-8.

Chemical & Physical Properties

Boiling Point	225ºC100 mm Hg(lit.)
Melting Point	44-46ºC(lit.)
Molecular Formula	C₁₂H₂₂D₂O₂
Molecular Weight	202.33
Flash Point	113ºC
Exact Mass	202.19000
PSA	37.30000
LogP	3.99190
InChIKey	POULHZVOKOAJMA-ZWGOZCLVSA-N
SMILES	CCCCCCCCCCCC(=O)O

Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-28
RIDADR	NONH for all modes of transport
WGK Germany	3

Synonyms

Lauric-2,2-d2 acid

2,2-di-2H-lauric acid

Dodecanoic acid-2,2-d2

2,2-Dideuteriododanoic acid

2,2-dideuterio-dodecanoic acid

2,2-Dideuterio-dodecansaeure

MFCD00053326

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