Introduction：Basic information about CAS 6989-38-4|Evodine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Evodine |
|---|
| CAS Number | 6989-38-4 | Molecular Weight | 329.347 |
|---|
| Density | 1.2±0.1 g/cm3 | Boiling Point | 507.0±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C18H19NO5 | Melting Point | 153-154ºC |
|---|
| MSDS | / | Flash Point | 260.4±30.1 °C |
|---|
Names
| Name | 1-[(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-3-buten-2 -ol |
|---|
| Synonym | More Synonyms |
|---|
Evodine BiologicalActivity
| Description | Evodine, the major limonoid of Evodiae Fuctus, is a potent P-gp inhibitor. Evodine has protection against glutamateinduced toxicity by preserving the antioxidant defense system[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Membrane Transporter/Ion Channel >>P-glycoprotein |
|---|
| References | [1]. Xia YY, et al. Simultaneous determination of evodiamine and evodine in Beagle dog plasma using liquidchromatography tandem mass spectrometry. J Asian Nat Prod Res. 2013;15(3):235-43. |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 507.0±50.0 °C at 760 mmHg |
|---|
| Melting Point | 153-154ºC |
|---|
| Molecular Formula | C18H19NO5 |
|---|
| Molecular Weight | 329.347 |
|---|
| Flash Point | 260.4±30.1 °C |
|---|
| Exact Mass | 329.126312 |
|---|
| PSA | 73.95000 |
|---|
| LogP | 3.26 |
|---|
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.612 |
|---|
| InChIKey | LNJTUUHDKCPQAA-UHFFFAOYSA-N |
|---|
| SMILES | C=C(C)C(O)COc1ccc2c(OC)c3ccoc3nc2c1OC |
|---|
| Storage condition | 2-8C |
|---|
Synonyms
| 1-[(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-3-buten-2-ol |
| 3-Buten-2-ol, 1-[(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl- |
| (-)-1'-(2-phenylethylene)-ditryptophenaline |
| (-)-1-(4,8-dimethoxy-furo[2,3-b]quinolin-7-yloxy)-3-methyl-but-3-en-2-ol |
| Evodine |
