CAS 60546-10-3|Gomisin D
Introduction：Basic information about CAS 60546-10-3|Gomisin D, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Gomisin D | ||
|---|---|---|---|
| CAS Number | 60546-10-3 | Molecular Weight | 530.564 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 698.5±55.0 °C at 760 mmHg |
| Molecular Formula | C28H34O10 | Melting Point | 194ºC |
| MSDS | / | Flash Point | 229.3±25.0 °C |
Names
| Name | (11S,12R,15S,24S,25S)-12,25-Dihydroxy-18,19,20-trimethoxy-11,12,24,25-tetramethyl-4,6,9,14-tetraoxapentacyclo[13.7.3.03,7.08,22.016,21]pentacosa-1(22),2,7,16,18,20-hexaen-13-one |
|---|---|
| Synonym | More Synonyms |
Gomisin D BiologicalActivity
| Description | Gomisin D, a lignan compound isolated from Fructus Schisandra, is a potential antidiabetic and anti-Alzheimer’s agent. Gomisin D inhibits UDP-Glucuronosyltransferases activity and scavenges ABTS(+) radicals. Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
| Target | UDP-Glucuronosyltransferases[1] |
| References | [1]. Zheng X, et al. A Rapid UPLC-MS Method for Quantification of Gomisin D in Rat Plasma and Its Application to a Pharmacokinetic and Bioavailability Study. Molecules. 2019 Apr 10;24(7). |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 698.5±55.0 °C at 760 mmHg |
| Melting Point | 194ºC |
| Molecular Formula | C28H34O10 |
| Molecular Weight | 530.564 |
| Flash Point | 229.3±25.0 °C |
| Exact Mass | 530.215210 |
| PSA | 122.14000 |
| LogP | 3.95 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.561 |
| InChIKey | VLLFEMVDMFTBHG-KMIFWYFFSA-N |
| SMILES | COc1cc2c(c(OC)c1OC)-c1c3cc4c(c1OCC(C)C(C)(O)C(=O)OC2C(C)(O)C(C)C3)OCO4 |
| Storage condition | 2-8℃ |
Synonyms
| (11S,12R,15S,24S,25S)-12,25-Dihydroxy-18,19,20-trimethoxy-11,12,24,25-tetramethyl-4,6,9,14-tetraoxapentacyclo[13.7.3.0.0.0]pentacosa-1(22),2,7,16,18,20-hexaen-13-one |
| (11R,12R,15S,24S,25S)-12,25-Dihydroxy-18,19,20-trimethoxy-11,12,24,25-tetramethyl-4,6,9,14-tetraoxapentacyclo[13.7.3.0.0.0]pentacosa-1(22),2,7,16,18,20-hexaen-13-one |
| 10,15-Propano-10H-1,3,4,9-tetraoxabenzo[3,4]cycloundec[1,2-e]inden-8(5H)-one, 6,7-dihydro-7,19-dihydroxy-12,13,14-trimethoxy-6,7,18,19-tetramethyl-, (6S,7R,10S,18S,19S)- |
| 10,15-Propano-10H-1,3,4,9-tetraoxabenzo[3,4]cycloundec[1,2-e]inden-8(5H)-one, 6,7-dihydro-7,19-dihydroxy-12,13,14-trimethoxy-6,7,18,19-tetramethyl-, (6R,7R,10S,18S,19S)- |
| Gomisin D |
