Introduction：Basic information about CAS 94987-08-3|Gypenoside XLIX, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Gypenoside XLIX |
|---|
| CAS Number | 94987-08-3 | Molecular Weight | 1047.227 |
|---|
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1105.1±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C52H86O21 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 306.9±27.8 °C |
|---|
Names
| Name | (3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-yl β-D-glucopyranoside |
|---|
| Synonym | More Synonyms |
|---|
Gypenoside XLIX BiologicalActivity
| Description | Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells[1]. |
|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Cell Cycle/DNA Damage >>PPARResearch Areas >>Inflammation/Immunology |
|---|
| Target | PPAR-α |
|---|
| References | [1]. Huang TH , et al. Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells. Eur J Pharmacol. 2007 Jun 22;565(1-3):158-65. |
|---|
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|
| Boiling Point | 1105.1±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C52H86O21 |
|---|
| Molecular Weight | 1047.227 |
|---|
| Flash Point | 306.9±27.8 °C |
|---|
| Exact Mass | 1046.566162 |
|---|
| PSA | 333.67000 |
|---|
| LogP | 5.46 |
|---|
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.615 |
|---|
| InChIKey | AFEVCSJFNQWWDF-AZFNEDKCSA-N |
|---|
| SMILES | CC(C)=CCCC(O)(COC1OC(CO)C(O)C(O)C1O)C1CCC2(C)C1CCC1C3(C=O)CCC(OC4OCC(O)C(OC5OCC(O)C(O)C5O)C4OC4OC(C)C(O)C(O)C4O)C(C)(C)C3CCC12C |
|---|
| Storage condition | 2-8C |
|---|
Synonyms
| (3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-yl β-D-glucopyranoside |
| Dammar-24-en-19-al, 3-[[O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy]-21-(β-D-glucopyranosyloxy)-20-hydroxy-, (3β)- |
| Gypenoside XLIX |
