CAS 478963-79-0|Calcium-Sensing Receptor Antagonists I

Introduction：Basic information about CAS 478963-79-0|Calcium-Sensing Receptor Antagonists I, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Calcium-Sensing Receptor Antagonists I BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Calcium-Sensing Receptor Antagonists I
CAS Number	478963-79-0	Molecular Weight	360.44900
Density	1.085g/cm3	Boiling Point	510.1ºC at 760 mmHg
Molecular Formula	C₂₃H₂₄N₂O₂	Melting Point	/
MSDS	/	Flash Point	262.299ºC

Names

Name	1-propan-2-yl-4-(4-propan-2-ylphenyl)-6-prop-2-ynoxyquinazolin-2-one
Synonym	More Synonyms

Calcium-Sensing Receptor Antagonists I BiologicalActivity

Description	Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors. IC50 value:Target: CaSRCalcium-Sensing Receptor Antagonists I is useful for osteoporosis and other bone conditions
Related Catalog	Signaling Pathways >>GPCR/G Protein >>CaSRResearch Areas >>Others
References	[1]. Widler, Leo et al. 1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists.Journal of Medicinal Chemistry(2010),53(5), 2250-2263.

Chemical & Physical Properties

Density	1.085g/cm3
Boiling Point	510.1ºC at 760 mmHg
Molecular Formula	C₂₃H₂₄N₂O₂
Molecular Weight	360.44900
Flash Point	262.299ºC
Exact Mass	360.18400
PSA	44.12000
LogP	4.77980
Index of Refraction	1.572
InChIKey	RXVZJHDMMKTKDR-UHFFFAOYSA-N
SMILES	C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C
Storage condition	2-8℃

Synonyms

CS-0307

1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-2(1H)-QUINAZOLINONE

Calcium-Sensing Receptor Antagonists I

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