CAS 820959-17-9|Acetyl tetrapeptide-5
Introduction：Basic information about CAS 820959-17-9|Acetyl tetrapeptide-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Acetyl tetrapeptide-5 | ||
|---|---|---|---|
| CAS Number | 820959-17-9 | Molecular Weight | 492.486 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1237.3±65.0 °C at 760 mmHg |
| Molecular Formula | C20H28N8O7 | Melting Point | / |
| MSDS | / | Flash Point | 702.1±34.3 °C |
Names
| Name | (2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid |
|---|---|
| Synonym | More Synonyms |
Acetyl tetrapeptide-5 BiologicalActivity
| Description | Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Angiotensin-converting Enzyme (ACE) |
| Target | ACE-1[1] |
| In Vitro | Acetyl tetrapeptide-5 (100 μg/mL) inhibits angiotensin-converting enzyme 1 (ACE-1) activity[1]. |
| References | [1]. Yun Wu, et al. Protective and Anti-Aging Effects of 5 Cosmeceutical Peptide Mixtures on Hydrogen Peroxide-Induced Premature Senescence in Human Skin Fibroblasts. Skin Pharmacol Physiol. 2021;34(4):194-202. [2]. Lijuan Zhang, et al. Cosmeceuticals and peptides. Clin Dermatol. 2009 Sep-Oct;27(5):485-94. [3]. Puig A , et al. "Eyeseryl® and Leuphasyl®: synthetic peptides as advanced cosmetic actives. Cosmet Sci Technol (2006): 164-75. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1237.3±65.0 °C at 760 mmHg |
| Molecular Formula | C20H28N8O7 |
| Molecular Weight | 492.486 |
| Flash Point | 702.1±34.3 °C |
| Exact Mass | 492.208099 |
| PSA | 245.25000 |
| LogP | -3.79 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.611 |
| InChIKey | ROTFCACGLKOUGI-JYJNAYRXSA-N |
| SMILES | CC(=O)NCCC(=O)NC(Cc1cnc[nH]1)C(=O)NC(CO)C(=O)NC(Cc1cnc[nH]1)C(=O)O |
| Storage condition | 2-8℃ |
Synonyms
| N-Acetyl-β-alanyl-L-histidyl-L-seryl-l-histidin |
| UNII-Y1DFQ308G8 |
| Eyeseryl |
| L-Histidine, N-acetyl-β-alanyl-L-histidyl-L-seryl- |
| N-Acetyl-β-alanyl-L-histidyl-L-seryl-L-histidine |
| Acetyl tetrapeptide-5 |
