Introduction：Basic information about CAS 18725-37-6|Dacisteine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM[1]. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation[2].
Related Catalog
Research Areas >>Metabolic Disease
Target
IC50: 1000 μM (NDM-1)[1]
In Vivo
Dacisteine is a preparing agent for treating or preventing cardiovascular and cerebrovascular diseases caused by platelet aggregation.
References
[1]. Cui-Gai Bai1, et al. Cysteine and Its Derivatives as New Delhi Metallo-beta-lactamase-1 Inhibitors. Current Enzyme Inhibition, 2015, 11, 46-57
[2]. FanKe, et al.Application of compound of thioether acid structure in preparing anti-platelet aggregation drugs. Patent WO2019007015A1.
Chemical & Physical Properties
Density
1.314g/cm3
Boiling Point
446.8ºC at 760 mmHg
Melting Point
114-116°C
Molecular Formula
C7H11NO4S
Molecular Weight
205.23200
Flash Point
224ºC
Exact Mass
205.04100
PSA
108.77000
LogP
0.24630
Vapour Pressure
3.13E-09mmHg at 25°C
Index of Refraction
1.522
InChIKey
HSPYGHDTVQJUDE-LURJTMIESA-N
SMILES
CC(=O)NC(CSC(C)=O)C(=O)O
Storage condition
Refrigerator
Safety Information
HS Code
2930909090
Customs
HS Code
2930909090
Summary
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles1
More Articles
Formation of the thioester, N,S-diacetylcysteine, from acetaldehyde and N,N'diacetylcystine in aqueous solution with ultraviolet light.
J. Mol. Evol. 17(2) , 103-7, (1981)
The thioester, N,S-diacetylcysteine, is formed during the illumination of phosphate buffered (pH 7.0) aqueous solutions of acetaldehyde and N,N'-diacetylcystine with ultraviolet light. The yield of N,...
