CAS 65710-07-8|Apramycin sulfate

Introduction:Basic information about CAS 65710-07-8|Apramycin sulfate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameApramycin sulfate
CAS Number65710-07-8Molecular Weight637.656
Density1.56Boiling Point949.8ºC at 760 mmHg
Molecular FormulaC21H43N5O15SMelting Point>168ºC (dec.)
MSDSChineseUSAFlash Point528.2ºC
Symbol
GHS08
Signal WordDanger

Names

NameApramycin sulfate salt
SynonymMore Synonyms

Apramycin sulfate BiologicalActivity

DescriptionApramycin sulfate is an aminoglycoside antibiotic mproduced by a strain of Streptomyces tenebrarius, used in veterinary practice.
Related CatalogSignaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection

Chemical & Physical Properties

Density1.56
Boiling Point949.8ºC at 760 mmHg
Melting Point>168ºC (dec.)
Molecular FormulaC21H43N5O15S
Molecular Weight637.656
Flash Point528.2ºC
Exact Mass637.247620
PSA41.99000
LogP3.82570
Appearance of Characterswhite to light yellow
InChIKeyWGLYHYWDYPSNPF-RQFIXDHTSA-N
SMILESCNC1C(OC2OC(CO)C(N)C(O)C2O)OC2CC(N)C(OC3C(N)CC(N)C(O)C3O)OC2C1O.O=S(=O)(O)O
Storage condition2-8°C
Water SolubilityH2O: soluble25mg/mL | Soluble in water.

Safety Information

Symbol
GHS08
Signal WordDanger
Hazard StatementsH360
Precautionary StatementsP201-P308 + P313
Personal Protective EquipmentEyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges
Hazard CodesT: Toxic;
Risk PhrasesR61;R35
Safety PhrasesS53-S26-S36/37/39-S45
RIDADRNONH for all modes of transport
WGK Germany3
HS Code29419000

Customs

HS Code29419000

Articles29

More Articles
Genomic analysis reveals distinct concentration-dependent evolutionary trajectories for antibiotic resistance in Escherichia coli.

DNA Res. 21(6) , 711-26, (2014)

Evolution of bacteria under sublethal concentrations of antibiotics represents a trade-off between growth and resistance to the antibiotic. To understand this trade-off, we performed in vitro evolutio...

Field trial evaluating changes in prevalence and patterns of antimicrobial resistance among Escherichia coli and Enterococcus spp. isolated from growing broilers medicated with enrofloxacin, apramycin and amoxicillin

Vet. Microbiol. 139(3-4) , 284-92, (2009)

The present study investigates, under field conditions, the influence of antimicrobial administration on prevalence and patterns of antimicrobial resistance among Escherichia coli and Enterococcus spp...

Enhancement of bacterial competitive fitness by apramycin resistance plasmids from non-pathogenic Escherichia coli.

Biol. Lett. 2(3) , 463-5, (2006)

The study of antibiotic resistance has in the past focused on organisms that are pathogenic to humans or animals. However, the development of resistance in commensal organisms is of concern because of...

Synonyms

Apramycin sulphate
Apramycin sulfate
(2R,3R,4S,5S,6S)-5-Amino-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)octahydropyrano[3,2-b]pyran-2-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol sulfate (1:1) (non-preferred name)
UNII-8UYL6NAZ3Q
(2R,3S,4R,4aR,6S,7R,8aS)-7-Amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)octahydropyrano[3,2-b]pyran-2-yl 4-amino-4-deoxy-α-D-glucopyranoside sulfate (1:1)
Apramycin (sulfate)
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