Introduction：Basic information about CAS 97399-91-2|Aristolactam AIIIa, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Aristolactam AIIIa |
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| CAS Number | 97399-91-2 | Molecular Weight | 281.263 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 521.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H11NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 268.9±30.1 °C |
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Names
| Name | Aristolactam AIIIa |
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| Synonym | More Synonyms |
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Aristolactam AIIIa BiologicalActivity
| Description | Aristolactam A IIIa (Sch 546909) is an aristolactam-type alkaloid that can be isolated from Glycosmis chlorosperma. Aristolactam A IIIa is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells[1]. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Protein Tyrosine Kinase/RTK >>DYRK |
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| References | [1]. Chia YC, et al. Aristolactams and dioxoaporphines from Fissistigma balansae and Fissistigma oldhamii. J Nat Prod. 2000 Aug;63(8):1160-3. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 521.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H11NO4 |
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| Molecular Weight | 281.263 |
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| Flash Point | 268.9±30.1 °C |
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| Exact Mass | 281.068817 |
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| PSA | 82.55000 |
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| LogP | 1.62 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.812 |
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| InChIKey | PFXGXKFPTAJYHV-UHFFFAOYSA-N |
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| SMILES | COc1c(O)cc2c3c(cc4ccc(O)cc4c13)NC2=O |
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Synonyms
| 2,9-Dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-one |
| Dibenz[cd,f]indol-4(5H)-one, 2,9-dihydroxy-1-methoxy- |
