CAS 49745-95-1|Dobutamine hydrochloride

Introduction：Basic information about CAS 49745-95-1|Dobutamine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Dobutamine hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles51
6. Synonyms

Common Name	Dobutamine hydrochloride
CAS Number	49745-95-1	Molecular Weight	337.841
Density	/	Boiling Point	527.7ºC at 760mmHg
Molecular Formula	C₁₈H₂₄ClNO₃	Melting Point	184-186ºC(lit.)
MSDS	ChineseUSA	Flash Point	169.8ºC
Symbol	GHS07, GHS08	Signal Word	Warning

Names

Name	dobutamine hydrochloride
Synonym	More Synonyms

Dobutamine hydrochloride BiologicalActivity

Description	Dobutamine Hcl(Dobutrex) is a sympathomimetic drug used in the treatment of heart failure and cardiogenic shock. Its primary mechanism is direct stimulation of β1 receptors of the sympathetic nervous system.
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Cardiovascular Disease
References	[1]. Dobutamine, From wikipedia

Chemical & Physical Properties

Boiling Point	527.7ºC at 760mmHg
Melting Point	184-186ºC(lit.)
Molecular Formula	C₁₈H₂₄ClNO₃
Molecular Weight	337.841
Flash Point	169.8ºC
Exact Mass	337.144470
PSA	72.72000
LogP	4.14970
InChIKey	BQKADKWNRWCIJL-UHFFFAOYSA-N
SMILES	CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1.Cl
Storage condition	2-8°C

Safety Information

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H302-H312-H332-H361
Precautionary Statements	P280
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22;R63
Safety Phrases	S22-S26-S36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	3

Articles51

Preventive and therapeutic effects of a beta adrenoreceptor agonist, dobutamine, in carrageenan-induced inflammatory nociception in rats.

Inflammation 37(5) , 1814-25, (2014)

We hypothesized that locally administrated β-adrenoreceptor agonist can modulate the inflammatory nociceptive parameters in carrageenan (CG)-induced peripheral inflammatory pain. This study was theref...

Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses.

Am. J. Vet. Res. 75(7) , 668-79, (2014)

To compare the effects of 2 NSAIDs (phenylbutazone and meloxicam) on renal function in horses.9 Thoroughbred or Standardbred mares (mean ± SD age, 5.22 ± 1.09 years [range, 2 to 12 years]; mean body w...

Dobutamine stress MRI for the assessment of coronary artery disease: initial clinical experience in Israel.

Isr. Med. Assoc. J. 15(5) , 205-9, (2013)

Over the past few years dobutamine stress magnetic resonance (DSMR) has proven its efficacy as an integral part of the diagnosis of coronary artery disease (CAD).To present the feasibility and safety ...

Synonyms

3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-b-phenylethylamine Hydrochloride

4-(2-{[4-(4-Hydroxyphenyl)-2-butanyl]amino}ethyl)-1,2-benzenediol hydrochloride (1:1)

EINECS 256-464-1

1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (1:1)

Dobutamine hydrochloride

3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine Hydrochloride

1,2-benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride

(±)-4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride

4-(2-{[4-(4-Hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol hydrochloride (1:1)

4-(2-{[3-(4-hydroxyphényl)-1-méthylpropyl]amino}éthyl)benzène-1,2-diol chlorhydrate

4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzol-1,2-diolhydrochlorid

(±)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine hydrochloride

4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzene-1,2-diol hydrochloride

rac Dobutamine Hydrochloride

(±)-4-[2-[[3-(p-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]pyrocatechol Hydrochloride

MFCD00153795

Dobutamine (hydrochloride)

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