CAS 186142-28-9|(Asn⁶⁷⁰,Leu6⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-676) trifluo

Introduction：Basic information about CAS 186142-28-9|(Asn⁶⁷⁰,Leu6⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-676) trifluo, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	(Asn⁶⁷⁰,Leu6⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-676) trifluoroacetate salt
CAS Number	186142-28-9	Molecular Weight	1179.237
Density	1.5±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₅₀H₇₈N₁₄O₁₉	Melting Point	/
MSDS	USA	Flash Point	/

Names

Name	[Asn670,Leu671]-Amyloid β/A4 Protein Precursor770 (667-676)
Synonym	More Synonyms

BiologicalActivity

Description	SEVNLDAEFR is a substrate for BACE1[1].
Related Catalog	Signaling Pathways >>Neuronal Signaling >>Beta-secretaseResearch Areas >>Neurological Disease
Target	BACE1[1]
References	[1]. Machálková M, et al. A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer's disease drug target β-secretase. Anal Bioanal Chem. 2018 Nov;410(28):7441-7448.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Molecular Formula	C₅₀H₇₈N₁₄O₁₉
Molecular Weight	1179.237
Exact Mass	1178.556763
PSA	562.34000
LogP	-1.78
Appearance of Characters	solid
Index of Refraction	1.646
InChIKey	JONOLKHIDOKDGP-RDICLXJSSA-N
SMILES	CC(C)CC(NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CCC(=O)O)NC(=O)C(N)CO)C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCN=C(N)N)C(=O)O
Storage condition	−20°C

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

Synonyms

(ASN670,LEU671)-APP770 (667-676)

H-Ser-Glu-Val-Asn

SEVNLDAEFR

A4 PROTEIN PRECURSOR770 (667-676)

SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG

H-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-OH

MFCD03097426

(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-676)

Recommended......