Introduction：Basic information about CAS 32780-32-8|validamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | validamine |
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| CAS Number | 32780-32-8 | Molecular Weight | 177.20 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 345.6±42.0 °C at 760 mmHg |
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| Molecular Formula | C7H15NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 162.8±27.9 °C |
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Names
| Name | validamine |
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| Synonym | More Synonyms |
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validamine BiologicalActivity
| Description | Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC50 value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme[1]. |
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| Related Catalog | Research Areas >>Metabolic Disease |
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| Target | IC50 value of 2.92mM[1] |
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| References | [1]. Takeuchi M, et al. Inhibitory effect of validamine, valienamine and valiolamine on activities of carbohydrases in rat small intestinal brush border membranes. Chem Pharm Bull (Tokyo). 1990 Jul;38(7):1970-2. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 345.6±42.0 °C at 760 mmHg |
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| Molecular Formula | C7H15NO4 |
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| Molecular Weight | 177.20 |
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| Flash Point | 162.8±27.9 °C |
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| Exact Mass | 177.100113 |
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| PSA | 106.94000 |
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| LogP | -2.36 |
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| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
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| Index of Refraction | 1.599 |
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| InChIKey | GSQYAWMREAXBHF-UOYQFSTFSA-N |
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| SMILES | NC1CC(CO)C(O)C(O)C1O |
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Safety Information
Customs
| HS Code | 2922199090 |
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| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| PT 141 |
| Pt141 Acetate |
| (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)-1,2,3-cyclohexanetriol |
| 1s-(1,2,4/3,5)-1-amino-5-hydroxymethyl-2,3,4-cyclohexantriol |
| 1,2,3-Cyclohexanetriol, 4-amino-6-(hydroxymethyl)-, (1R,2S,3S,4S,6R)- |
| MFCD08063357 |
| (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol |
| Bremelanotide Acetate |
| Validamine |
| 1-Amino-5-(hydroxymethyl)-1,5,6-trideoxy-D-chiro-inositol |
| (1R,2S,3S,4S)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol |
| PT-141 (BREMELANOTIDE) |
| Bremelanotide,PT141,Acetate |
| 1-Amino-1,5,6-trideoxy-5-(hydroxymethyl)-D-chiro-inositol |
