Introduction：Basic information about CAS 18797-80-3|Acetylcorynoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Acetylcorynoline |
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| CAS Number | 18797-80-3 | Molecular Weight | 409.432 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 499.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C23H23NO6 | Melting Point | / |
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| MSDS | / | Flash Point | 255.7±28.7 °C |
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Names
| Name | Acetylcorynoline |
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| Synonym | More Synonyms |
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Acetylcorynoline BiologicalActivity
| Description | Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs)[1]. Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase[1]. |
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| References | [1]. Fu RH, et al. Acetylcorynoline attenuates dopaminergic neuron degeneration and α-synuclein aggregation in animal models of Parkinson's disease. Neuropharmacology. 2014 Jul;82:108-20. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 499.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C23H23NO6 |
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| Molecular Weight | 409.432 |
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| Flash Point | 255.7±28.7 °C |
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| Exact Mass | 409.152527 |
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| PSA | 66.46000 |
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| LogP | 4.05 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.667 |
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| InChIKey | PUHCFWFODBLSAP-WWNPGLIZSA-N |
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| SMILES | CC(=O)OC1Cc2cc3c(cc2C2N(C)Cc4c(ccc5c4OCO5)C12C)OCO3 |
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| Storage condition | 2-8C |
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Synonyms
| (5bR)-6t-acetoxy-5b,13-dimethyl-(5br,12bc)-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine |
| [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol, 5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, acetate (ester), (5bR,6S,12bR)- |
| corynoline acetate |
| (+)-O-acetyl-corynoline |
| N1513 |
| Acetylcorynoline |
| (+)-Corynolin-acetat |
| O-Acetyl-13-methylchelidonine |
| O-acetyl-13-methyl-chelidonine |
| (+)-Corynolin-O-acetat |
