Introduction：Basic information about CAS 4608-49-5|Larixyl acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Larixyl acetate |
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| CAS Number | 4608-49-5 | Molecular Weight | 348.51900 |
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| Density | 1.00±0.1 g/cm3 (20ºC 760 Torr) | Boiling Point | 419.3±28.0 °C |
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| Molecular Formula | C22H36O3 | Melting Point | 82ºC |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | larixyl acetate |
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| Synonym | More Synonyms |
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Larixyl acetate BiologicalActivity
| Description | Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction[1][2]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>TRP ChannelResearch Areas >>InfectionResearch Areas >>Neurological Disease |
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| Target | hTRPC6:0.58 μM (IC50) hTRPC3:6.83 μM (IC50) |
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| References | [1]. Urban N, et al. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor. Mol Pharmacol. 2016 Jan;89(1):197-213. [2]. Chen X, et al. The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction. J Neuroinflammation. 2019 Jan 31;16(1):21. |
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Chemical & Physical Properties
| Density | 1.00±0.1 g/cm3 (20ºC 760 Torr) |
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| Boiling Point | 419.3±28.0 °C |
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| Melting Point | 82ºC |
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| Molecular Formula | C22H36O3 |
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| Molecular Weight | 348.51900 |
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| Exact Mass | 348.26600 |
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| PSA | 46.53000 |
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| LogP | 5.04400 |
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| Index of Refraction | 1.4826 (589.3 nm, 20℃) |
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| Storage condition | ?20°C |
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| Larixylacetat |
| Larixol-monoacetat |
| 6-Acetyllarixol |
