CAS 189696-20-6|Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

Introduction：Basic information about CAS 189696-20-6|Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles1
6. Synonyms

Common Name	Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH
CAS Number	189696-20-6	Molecular Weight	1155.08000
Density	/	Boiling Point	/
Molecular Formula	C₅₀H₆₂N₁₀O₂₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	/

Names

Name	7-Methoxycoumarin-4-acetyl-Asp-Glu-Val-Asp-Ala-Pro-(2,4-dinitrophenyl)Lys
Synonym	More Synonyms

Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH BiologicalActivity

Description	Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Apoptosis >>Caspase
Target	Caspase-3
References	[1]. Fertig Georg. Method for the detection of the apoptosis activated cysteine protease Caspase 3 by specific antibody-binding and fluorescence enzyme assay. EP0955377A1

Chemical & Physical Properties

Molecular Formula	C₅₀H₆₂N₁₀O₂₂
Molecular Weight	1155.08000
Exact Mass	1154.40000
PSA	487.22000
LogP	3.32010
InChIKey	YOUVSUDOGAVRQX-AEAFXXELSA-N
SMILES	COc1ccc2c(CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)N3CCCC3C(=O)NC(CCCCNc3ccc([N+](=O)[O-])cc3[N+](=O)[O-])C(=O)O)C(C)C)cc(=O)oc2c1

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Articles1

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis.

Nature 380 , 723, (1996)

Binding of Fas ligand or an agonistic anti-Fas antibody induces apoptosis in Fas-bearing cells. The interleukin-1Beta-converting enzyme (ICE) is a cysteine protease that is involved in apoptosis induc...

Synonyms

Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

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